Acoustic Radiation Force Impulse Elastography in Determining the Effects of Type 1 Diabetes on Pancreas and Kidney Elasticity in Children

Sağlam, Dilek; Bilgici, Meltem Ceyhan; Kara, Cengiz; Yılmaz, Gülay Can; Çamlıdağ, İlkay

doi:10.2214/ajr.17.18170

Cited by 20 publications

(16 citation statements)

References 18 publications

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“…This finding agrees with our results for that region. They reported Vs of 1.09 ± 0.22 m/s for the body of the pancreas in healthy control subjects and 0.99 ± 0.25 m/s for patients with type 1 diabetes – values slightly lower than we found in our patients [7].…”

Section: Discussioncontrasting

confidence: 87%

“…Nevertheless, in contrast to their study, we did not find any correlation between Vs and BMI. Nor did we determine a correlation between the Vs and the duration of diabetes ( p = 0.7534), a finding which agrees with the results published by Saglam et al [7].…”

Section: Discussionsupporting

confidence: 87%

“…Concerning type 1 diabetes, a recent study on children and adolescents did not show any increased values in those with T1D. However, that study looked only at the body of the pancreas [7].…”

Section: Introductionmentioning

confidence: 99%

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Ultrasound point shear wave elastography of the pancreas: comparison of patients with type 1 diabetes and healthy volunteers – results from a pilot study

et al. 2018

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BackgroundThe aims of this study were to establish shear wave elastography of the pancreas by comparing measurements in patients with type 1 diabetes (T1D) and healthy volunteers and to consider whether this method could contribute to the screening or prevention of T1D.MethodsThis pilot study included 15 patients with T1D (10 men, 5 women) and 15 healthy volunteers (10 men, 5 women) as controls. Measurements were performed with a Siemens Acuson S3000 (Siemens Healthcare, Erlangen, Germany) using a 6C1 convex transducer and the Virtual Touch™ tissue quantification (VTQ) method.ResultsThe mean shear wave velocity of the head of the pancreas was 1.0 ± 0.2 m/s (median: 1.1 m/s) for the study group and likewise 1.0 ± 0.2 m/s (median: 0.9 m/s) for the control group. Velocities of 1.2 ± 0.2 m/s (median: 1.2 m/s) were measured in the body of the pancreas in both groups. There was a significant difference between the values obtained in the tail of the pancreas: patients 1.1 ± 0.1 m/s (median: 1.0 m/s) versus controls 0.9 ± 0.1 m/s (median: 0.8 m/s) (p = 0.0474). The mean value in the whole pancreas of the study group was not significantly above that of the control group: 1.1 ± 0.1 m/s (median: 1.0 m/s) versus 1.0 ± 0.1 m/s (median: 1.0 m/s) (p = 0.2453).ConclusionsSonoelastography of the pancreas revealed no overall difference between patients with T1D and healthy volunteers. Patients with T1D showed higher values only in the tail segment. Future studies need to determine whether specific regional differences can be found in a larger study population.

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Section: Discussioncontrasting

confidence: 87%

Section: Discussionsupporting

confidence: 87%

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Ultrasound point shear wave elastography of the pancreas: comparison of patients with type 1 diabetes and healthy volunteers – results from a pilot study

et al. 2018

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“…Another study evaluating [37] the kidneys' renal cortical stiffness in Type 2 diabetes with grade 3-4 diabetic nephropathy showed that SWV was also higher than that in the control subjects. Saglam et al [38] evaluated the effects of Type 1 diabetes on renal cortical elasticity. They did not find any significant difference in SWV between patients with Type 1 diabetes and healthy subjects.…”

Section: Discussionmentioning

confidence: 99%

Determining the effects of excess weight on renal cortical stiffness in children and adolescents with point Shear Wave Elastography

Karaman

Kardaş

2021

Med Ultrason

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Aim: To determine the early effects of excess weight on renal cortical stiffness in children and adolescents using point shear wave elastography (pSWE). Materials and methods: One hundred and forty-six overweight and obese children (43.2% male; mean age, 12.6±2.9 years: range 4.3-18) and 48 lean children (27.1% male: mean age, 12.4±3.4: range 4.8-18.9) were included in the study and control group, respectively. pSWE measurements of the two kidneys were performed. The mean value of shear wave velocity was compared between groups. Results: The mean shear wave velocity was 2.79±0.53 m/s for the control subjects and 3.09±0.59 m/s for the overweight-obese subjects. The differences between the two groups were sta-tistically significant (p=0.001). There was no correlation between shear wave velocity and age or depth. A positive correlation was found between shear wave velocity and body mass index, body mass index-standard deviation score. Conclusion: Renal cortical stiffness was higher in children with excess weight than in lean children. This study is the first attempt at applying pSWE to investigate the early adverse effects of excess weight.

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“…Tüm bu hastalıklarsa böbrek KS artmaktadır. Tip I ve Tip II DM olan hastalarda normo-albuminurik döneminde böbrek KS kontrollere benzer iken, albumunüri varlığında böbrek KS arttığı bildirilmiştir(30)(31)(32). ElastPQ tekniği doku elastikiyetini değerlendiren son elastografi tekniğidir ve çocuklarda böbrek hastalıklarda doku elastikiyeti bu teknik ile ilk kez 2016 yılında Xu ve ark(33) tarafından yapılmıştır(33).…”

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Renal Cortical Stiffness Obtained by ElastPQ Technique is Significantly Increased in Children with Newly Diagnosed Hypertension

Koç¹,

Cilsal²

2019

jcp

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GİRİŞ: Bu çalışmada hipertansiyon (HT) olan çocuklarda, elastografi point qantifiation (ElastPQ) incelemesi ile elde edilen böbrek kortikal sertlik (KS) değişiminin değerlendirilmesi ve bu hastalardaki KS ile ilişkili parametrelerin tespit edilmesi amaçlandı. GEREÇ ve YÖNTEM: Çalışmaya 7-16 yaş aralığında okul çağında yeni tanı HT olan 40 çocuk ve 20 sağlıklı kontrol alındı. Rutin anamnez, fizik muayene ve laboratuvar incelemelerine ek olarak böbrek ultrasonografisi (USG) yapıldı. ElastPQ incelemesi ile böbrek KS düzeyi ölçüldü. BULGULAR: HT olan hastalarda; sistolik kan basıncı (SKB), diyastolik kan basıncı (DKB), nabız basıncı (PP), LDL kolesterol ve trigliserid düzeyleri, böbrek kortikal kalınlık ve KS değerleri sağlıklı kontrollere göre belirgin olarak yüksekti (p<0,05 her biri için). Böbrek KS ile tek değişkenli analizde SBP, DBP, PP ve böbrek kortikal kalınlık ile pozitif ve HDL ile negatif olarak ilişkili olduğu bulundu.Lineer regresyon analizinde, bu parametrelerden sadece SKB böbrek KS ile yakın olarak ilişkili olduğu tespit edildi (p<0,001 vs. β=0,395). SONUÇ: Yeni tanı HT olan çocuklarda ElastPQ tekniği ile elde edilen böbrek KS artar. Çalışmamızın sonucuna göre, HT olan çocuklarda hedef organ hasarının erken belirlemesinde böbrek KS bir kullanılabileceği kanısına varıldı. Ancak bu bulgu için ek çalışmaların yapılması gerektiği düşünüldü.

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Acoustic Radiation Force Impulse Elastography in Determining the Effects of Type 1 Diabetes on Pancreas and Kidney Elasticity in Children

Cited by 20 publications

References 18 publications

Ultrasound point shear wave elastography of the pancreas: comparison of patients with type 1 diabetes and healthy volunteers – results from a pilot study

Ultrasound point shear wave elastography of the pancreas: comparison of patients with type 1 diabetes and healthy volunteers – results from a pilot study

Determining the effects of excess weight on renal cortical stiffness in children and adolescents with point Shear Wave Elastography

Renal Cortical Stiffness Obtained by ElastPQ Technique is Significantly Increased in Children with Newly Diagnosed Hypertension

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