Acne Vulgaris

Cordain, Loren; Lindeberg, Staffan; Hurtado, Magdalena; Hill, Kim; Eaton, S. Boyd; Brand‐Miller, Jennie

doi:10.1001/archderm.138.12.1584

Cited by 426 publications

(127 citation statements)

References 86 publications

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“…This study indicated that the BMI is a potential prognostic factor as pointed out for other diseases including acne vulgaris [13]. This indication is important in the sense that, unlike age and sex, it raises the question of intervention, so further research directed toward confirmation of this association should be performed.…”

Section: Discussionmentioning

confidence: 78%

Prognostic Factor Analysis for Plaque Psoriasis

Sakai

Matsui²,

Fukushima³

et al. 2005

Dermatology

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Background: Little is known about the long-term prognostic factors which affect clinical outcomes after the diagnosis of psoriasis. Objective: To identify the prognostic factors which predict long-term outcomes after diagnosis. Methods: Patients’ clinical characteristics at diagnosis were associated with long-term prognosis using the logistic regression method for 169 psoriasis patients (median follow-up time 11.6 years). Results: The factors age ≧40 [odds ratio 0.27, 95% confidence interval (CI) 0.10–0.72, p = 0.0091], male (odds ratio 2.67, 95% CI 1.02–7.00,p = 0.0459) and BMI ≧25 (odds ratio 2.74, 95% CI 1.01–7.42, p = 0.0480) had significant effects on long-term prognosis after diagnosis. A simple prognostic index based on these factors was proposed. Conclusions: Three major prognostic factors were identified. The proposed index may be useful in the design of future clinical trials for psoriasis and in the selection of appropriate therapeutic approaches for individual patients.

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Section: Discussionmentioning

confidence: 78%

Prognostic Factor Analysis for Plaque Psoriasis

Sakai

Matsui²,

Fukushima³

et al. 2005

Dermatology

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“…It also participates in increasing the effect of circulating androgens. A variety of clinical studies showing that a high glycemic load diet plays a role in acne exacerbation and, inversely, that a low glycemic load diet might improve acne, provide further support for this theory [4,5,6,7,8,9]. There is also histopathological and immunohistochemical evidence that a low glycemic load diet reduces the size of sebaceous glands, decreases inflammation and diminishes the expression of proinflammatory interleukin 8 and sterol regulatory element binding protein 1 which is the key transcription factor of lipid biosynthesis [9].…”

Section: Introductionmentioning

confidence: 99%

“…Other factors including cosmetics, environment, hormones and stress are also involved in the development of acne. Although dietary factors have long been considered unimportant, accumulative evidence supports the role of nutritional factors in acne [2,3,4,5,6,7,8,9]. The apparent absence of acne in native non-Westernized populations, e.g.…”

Section: Introductionmentioning

confidence: 99%

“…The apparent absence of acne in native non-Westernized populations, e.g. the Kitavan Islanders of Papua New Guinea and the Aché hunter-gatherers of Paraguay [6], has led to the proposal that high glycemic loads in the Western diet could have a role in acne, perhaps through hyperinsulinemia leading to increased androgens, altered retinoid signaling and increased insulin-like growth factor 1 (IGF-1) [6,7,8]. IGF-1 stimulates basal keratinocyte proliferation and sebum production.…”

Section: Introductionmentioning

confidence: 99%

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Acne and Whey Protein Supplementation among Bodybuilders

Simonart¹

2012

Dermatology

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Accumulative evidence supports the role of nutritional factors in acne. I report here 5 healthy male adult patients developing acne after the consumption of whey protein, a favorite supplement of those engaged in bodybuilding. These observations are in line with biochemical and epidemiological data supporting the effects of milk and dairy products as enhancers of insulin/insulin-like growth factor 1 signaling and acne aggravation. Further prospective studies are required to determine the possible role of dietary supplements in the fitness and bodybuilding environment.

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“…1,2,3 Among these conditions are ailments as diverse as type 2 diabetes (T2D), CVD, 4 Alzheimer's disease (AD), 5,6,7 acne, 8,9 gout, 10,11,12 erectile dysfunction, 13 polycystic ovarian syndrome (PCOS) 14 and conditions that are typically deemed 'idiopathic', such as vertigo and tinnitus. 15,16,17 A growing body of evidence suggests that these wide-ranging and seemingly unconnected conditions can, in fact, be linked to a common underlying cause: metabolic derangement resulting primarily from chronic hyperinsulinemia, and its eventual end point, insulin resistance (IR).…”

Section: Introductionmentioning

confidence: 99%