Acne of the fulminans type following testosterone therapy in three excessively tall boys

Raised serum 11‐deoxycortisol in men with persistent acne vulgaris

“…In one other study the DHEAS and testosterone were no different from controls but the mean SHBG was reduced in the acne patients (Palatsi et al, 1986). Normal androgen values were obtained by others (Forstrom et al, 1974;Van der Meeren & Thijssen, 1984;Pochi et a/., 1965;Sultan et al, 1986;Schmidt et al, 1990). Although Schmidt et al (1990) did not find raised androgens in their male patients they did note increased levels of cortisol.…”

“…It is, however, accepted that acne is androgen related. It is commonly associated with puberty when androgens are increasing, is exacerbated by androgens (Traupe et al, 1988) and alleviated by anti-androgens in females (Adashi, 1990) and males (Misch et al, 1986). Patients with complete androgen insensitivity have undetectable sebum production and do not have acne (Imperato-McGinley et al, 1993).…”

Acne fulminans (acute febrile ulcerative conglobate acne) treated with isotretinoin: a case report

“…We have found 13 eases reported since then [7,8,[13][14][15][16][17][18][19]. The cause of AF is unknown.…”

Diagnostik und Therapie des Hypogonadismus bei erwachsenen M�nnern

“…Die Akne ging mit vermehrter 7Seborrhö einher. Eine Acne fulminans trat darüber hinaus bei eugonadalen Jugendlichen auf, die zur Behandlung eines überschießenden Längen-wachstums Testosteronenantat erhalten hatten [29]. Im Gegensatz zu der Verabreichung von Testosteron bei Männern mit normalen Testosteronwerten führt die Substitution hypogonadaler Männer seltener zur Akne.…”