Accurate analysis of selenium in water and serum using ETV-ICP-MS with isotope dilution

Accurate determination of selenium in blood serum by isotope dilution analysis using inductively coupled plasma collision cell mass spectrometry with xenon as collision gas

“…Turner et al reported an optimised temperature program in ETV-ICP-IDMS which allowed the elimination of polyatomic interferences originating from the sample matrix but not the Ar 2 + dimers. 10 Hence, only two minor abundant isotopes, 77 Se and 82 Se, could be used for IDA. Moreover, this sample introduction technique generates short transient signals which make isotope ratio measurements less precise than by continuous sample introduction.…”

Determination of selenium in biological materials by isotope dilution analysis with an octapole reaction system ICP-MS

“…[10][11][12][13] The determination of selenium in biological matrices by IDA-ICP-MS has been reported using a range of sample introduction systems such as pneumatic nebulisation, 14,15 hydride generation 15,16 and, more recently, electrothermal vaporization. 17,18 Nevertheless, these works have reported a series of disadvantages. Thus, Janghorbani et al 15 reported isotope ratio precisions around 1% using pneumatic nebulisation or hydride generation and measured the less abundant Se isotopes ( 74 Se, 77 Se and 82 Se isotopes) in order to avoid Ar 2 interferences.…”

Uncertainty contributions to species specific isotope dilution analysis. Part 2. Determination of methylmercury by HPLC coupled with quadrupole and multicollector ICP-MS

“…The estimation of the uncertainty associated with an analytical measurement is increasingly being recognised as an essential part of the measurement process, allowing improved intercomparison of analytical results, 1 and is a requirement for ISO accredited methods. 2 Isotope dilution analysis (IDA), which is regarded as a definitive analytical technique 3 because the precision and accuracy obtainable are unsurpassed by alternative analytical methods, 4 allows the estimation of a measurement uncertainty which is related directly to SI units, and therefore meets the highest metrological standards. 5 The calculation of an uncertainty budget also aids the development of an analytical method by allowing the analyst to identify which areas of the measurement process provide the major contributions to the overall measurement uncertainty and therefore focus on these areas in order to minimise the uncertainty estimate.…”