Accuracy of needle biopsy of breast lesions visible on ultrasound: Audit of fine needle versus core needle biopsy in 3233 consecutive samplings with ascertained outcomes

Abstract

FNAC and CNB were generally performed in different patients, thus our study reported indirect comparisons of these tests. Although FNAC performed well (except for relatively high inadequacy), CNB had significantly better performance based on measures of sensitivity, but this was associated with lower specificity for CNB relative to FNAC. Overall, CNB is the more reliable biopsy method for sonographically-visible lesions; where FNAC is used as the first-line test, inadequate or inconclusive FNAC can be largely resolved by using repeat sampling with CNB.

One-day core needle biopsy in a breast clinic: 4 years experience

“…The inconclusive rate of 9.2% falls in line with two large series reporting inconclusive rates of 4.3% and 7% [4,3], and the review by Willems et al describing a 1% inconclusive rate [8]. Sensitivity of 96.9% is similar to the 93% and 96% found by the two series [4,3]. Specificity of 99.4% is also similar to the 88% and 100% they describe [4,3].…”

“…CNB is considered to have superior accuracy and especially a lower rate of inconclusive pathologic diagnoses [2][3][4][5][6][7] and therefore less additional biopsies. FNAC has the advantage of speed, where CNB conventionally requires overnight processing.…”

Cytomorphologic Patterns of Breast Lesions in Sudanese Patients: Lessons Learned from Fine Needle Aspiration Cytology

“…Recently many authors recommended the use of Core needle biopsy (CNB) as it is considered of significant diagnostic accuracy, correct histology typing, and tumor grading, especially in lesions that are not definitively benign or malignant, non-palpable and/or calcified lesions (Garg et al, 2003;Hukkinen et al, 2008). Therefore, the use of CNB was recommended in the evaluation of breast lumps instead of FNAC (Brancato, 2012). However in low resource setting country like Sudan CNB is not routinely and widely used.…”

“A Study of Tru-Cut Biopsy and Fnac in a Clinically Palpable Breast Lump"

“…However much concern is given to the malignant lesions of the breast, as breast malignancy is one of the commonest malignancy in women throughout the world. 1 Breast lungs constitutes significant number of cases seen in surgical cut patient departments and frequently the need arises to distinguish between benign and malignant lumps prior to definitive treatment. 2 In recent past FNAC and Tru-cut biopsy has replaced incisional or excisional biopsy in diagnosing a breast lumph, because of its distinct advantages like out patient procedure, cost effectiveness, no need general anaesthesia less pain compared to incisional and excisional biopsy.…”