2017
DOI: 10.1186/s12882-017-0539-0
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Abstract: BackgroundThere is still an ongoing discussion on the prognostic value of cystatin C in assessment of kidney function. Accordingly, the present study aimed to conduct a meta-analysis to provide evidence for the prognostic value of this biomarker for acute kidney injury (AKI) in children.MethodsAn extensive search was performed in electronic databases of Medline, Embase, ISI Web of Science, Cochrane library and Scopus until the end of 2015. Standardized mean difference (SMD) with a 95% of confidence interval (9… Show more

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Cited by 56 publications
(45 citation statements)
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“…There are few studies of prognostic value of serum cystatin C in children with diabetes, yet, most studies evaluated cystatin C in children with acute kidney injury. The 2017 meta-analysis of Nakhjavan-Shahraki et al showed that serum cystatin C is potentially a more sensitive marker of acute kidney damage in children compared to serum creatinine [11].…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…There are few studies of prognostic value of serum cystatin C in children with diabetes, yet, most studies evaluated cystatin C in children with acute kidney injury. The 2017 meta-analysis of Nakhjavan-Shahraki et al showed that serum cystatin C is potentially a more sensitive marker of acute kidney damage in children compared to serum creatinine [11].…”
Section: Discussionmentioning
confidence: 99%
“…Recent studies showed that cystatin C is a valuable marker for acute kidney injury in pediatric population and even helps to stratify CVD risk in children with chronic kidney disease [11,12]. However, in the SEARCH for Diabetes in Youth study higher levels of cystatin C were found in healthy subjects compared to type 1 and type 2 diabetes patients [13].…”
Section: Introductionmentioning
confidence: 99%
“…A recent meta-analysis of four studies in children showed an AUROC of 0.85 (95% CI 0.81-0.88) for urinary cystatin C [68], while this marker was less accurate for the prediction of AKI in adults (AUROC 0.64, 95% CI 0.62-0.66) [69]. This meta-analysis was hampered by heterogeneity across the studies, in particular, lack of exclusion of pre-renal azotemia in many studies [69].…”
Section: Low-molecular Weight Proteinuria As Marker Of Acute Kidney Imentioning
confidence: 99%
“…The method of data extraction has been precisely reported in previous studies done by authors of the present study (Ebrahimi et al, 2014[ 9 ]; Ghelichkhani et al, 2016[ 14 ]; Hassanzadeh‐Rad et al, 2016[ 16 ]; Hosseini et al, 2015[ 19 ][ 20 ], 2016[ 21 ]; Izadi et al, 2016[ 24 ][ 25 ]; Nakhjavan-Shahraki et al, 2017[ 33 ]; Rahimi-Movaghar et al, 2016[ 35 ]; Safari et al, 2016[ 37 ]; Yousefifard et al, 2016[ 47 ][ 48 ][ 49 ][ 50 ]). In summary, search results were combined and same references were excluded using EndNote (version X5, Thomson Reuters, 2011).…”
Section: Methodsmentioning
confidence: 57%