ObjectivesThis systematic review focuses on the role of the intensity of fear in patient’s delay in cancer and in myocardial infarction.MethodsIn a search of literature published between 1990 and June 2009, 161 articles were found. After the use of inclusion and exclusion criteria, 11 articles in cancer and 4 articles in myocardial infarction remained.ResultsHigh levels of fear are associated with earlier help-seeking in both diseases; for low levels of fear, the picture is unclear.ConclusionThe level of fear is an important factor, which should be taken into account when facilitating help-seeking by patients.