AC biosusceptometry in the study of drug delivery

Biomagnetic Methods: Technologies Applied to Pharmaceutical Research

“…applied field), amount of ferromagnetic material and distance among the sensors and the ferromagnetic sample (9,11,85). ACB sensors are designed to detect magnetic field around 1 μT and have important advantages in comparison with other biomagnetic measurement devices, since they are robust, easy to construct, allow for easy assembly of axial and planar gradiometer, don't need to operate in magnetically shielded rooms, and allow for simplification of electronic instrumentation.…”

“…ACB sensors are, nowadays, designed to suit a wide range of biological applications (9,11,92,93). These magnetic sensors are composed of pairs of induction coils separated by a fixed baseline; each pair consists of excitation (outer) and detection (inner) coils in a first-order gradiometric configuration that provides good signal-to-noise properties (Fig.…”

“…In order to overcome such technical limitations, alternative methods based on biomagnetic field detection have been developed (8)(9)(10). The measurement of magnetic field produced within the human body is referred as biomagnetism.…”

Enteric Coated Magnetic HPMC Capsules Evaluated in Human Gastrointestinal Tract by AC Biosusceptometry

“…ACB uses induction coils for recording the magnetic flux variation obtained from the response of a magnetic material ingested (18). The ACB showed accuracy to evaluate physiologically different parameters of GI tract (16,19Y22) as well as to obtain the magnetic images in vitro (23).…”

“…A multisensor ACB system was implemented to characterize the disintegration process of tablets in vitro and in the human stomach, through the acquisition of magnetic signals (17). In addition, this system was also employed to monitor magnetic tablets in GI tract and to image the disintegration process, introducing a novel technique in imaging of the biological systems (18,24,25).…”