Abstract 789: Multi-targeted novel 5-substituted pyrrolo[3,2-<i>d</i>]pyrimidines with tumor-selective targeting and inhibition of cytosolic<i>de novo</i>purine biosynthesis and mitochondrial one-carbon metabolism

Tong, Nian; Shah, Khushbu; Gangjee, Aleem; O’Connor, Carrie; Porvirk, Adrianne W.; Dekhne, Aamod; Hou, Zhanjun; Matherly, Larry H.

doi:10.1158/1538-7445.sabcs18-789

Molecular and Cellular Biology / Genetics 2019

DOI: 10.1158/1538-7445.sabcs18-789

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Abstract 789: Multi-targeted novel 5-substituted pyrrolo[3,2-d]pyrimidines with tumor-selective targeting and inhibition of cytosolicde novopurine biosynthesis and mitochondrial one-carbon metabolism

Nian Tong

Khushbu Shah

Aleem Gangjee

et al.

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Abstract 789: Multi-targeted novel 5-substituted pyrrolo[3,2-d]pyrimidines with tumor-selective targeting and inhibition of cytosolicde novopurine biosynthesis and mitochondrial one-carbon metabolism

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