Absolute bioavailability of lead acetate and mining waste lead in rats

Bioaccessibility versus Bioavailability of Essential (Cu, Fe, Mn, and Zn) and Toxic (Pb) Elements from Phyto Hyperaccumulator Pistia stratiotes: Potential Risk of Dietary Intake

“…However, according to the current evaluations of the Joint FAO/WHO Expert Committee on Food Additives, there is no safe threshold limit for Pb intake, and even a negligible portion of this toxic metal can produce harmful effects. With regard to Pb absolute bioavailability (ABAV), our findings are consistent with the results of soil-bound Pb ABAV based on bone and liver data . A higher ABAV (approximately 3%) can be estimated on the basis of blood Pb values.…”

Bioaccessibility versus Bioavailability of Essential (Cu, Fe, Mn, and Zn) and Toxic (Pb) Elements from Phyto Hyperaccumulator Pistia stratiotes: Potential Risk of Dietary Intake

“…However, according to the current evaluations of the Joint FAO/WHO Expert Committee on Food Additives, there is no safe threshold limit for Pb intake, and even a negligible portion of this toxic metal can produce harmful effects. With regard to Pb absolute bioavailability (ABAV), our findings are consistent with the results of soil-bound Pb ABAV based on bone and liver data . A higher ABAV (approximately 3%) can be estimated on the basis of blood Pb values.…”

In vivo oral bioavailability of Pb sequestered in metal rich granules in bivalves

“…Another approach for estimation of ABA is to compare Pb accumulation in a target organ (normally blood Pb levels) in animals that have been fed Pb-containing food with those subjected to intravenous Pb administration (assumed to be 100% bioavailable). Comparing with intravenous administration of Pb, ABA of Pb-acetate to rats varied depending on the organ considered between 7 and 15% and that of mine waste soil was 0.4-2.7% (Freeman et al, 1994).…”

Dietary Lead and Phosphate Interactions Affect Oral Bioavailability of Soil Lead in the Mouse

“…Evaluation of Pb RBA estimates obtained in earlier studies in rodents should be examined with respect to dietary P and Ca levels and their molar ratio. For example, earlier studies of soil Pb bioavailability in rats have used both a natural ingredient diet and a purified diet (AIN-76A) with a higher P level. , In analyses reported here, RBA estimates for Pb in NIST SRM 2710a used data obtained from mice that consumed diets with identical P levels. Discordant levels of P in diets which affected the slope of regression lines would affect the calculation of the ratio used to estimate RBA.…”

Bioaccessibility versus Bioavailability of Essential (Cu, Fe, Mn, and Zn) and Toxic (Pb) Elements from Phyto Hyperaccumulator Pistia stratiotes: Potential Risk of Dietary Intake

“…However, according to the current evaluations of the Joint FAO/WHO Expert Committee on Food Additives, there is no safe threshold limit for Pb intake, and even a negligible portion of this toxic metal can produce harmful effects. With regard to Pb absolute bioavailability (ABAV), our findings are consistent with the results of soil-bound Pb ABAV based on bone and liver data . A higher ABAV (approximately 3%) can be estimated on the basis of blood Pb values.…”

In vivo oral bioavailability of Pb sequestered in metal rich granules in bivalves

“…Another approach for estimation of ABA is to compare Pb accumulation in a target organ (normally blood Pb levels) in animals that have been fed Pb-containing food with those subjected to intravenous Pb administration (assumed to be 100% bioavailable). Comparing with intravenous administration of Pb, ABA of Pb-acetate to rats varied depending on the organ considered between 7 and 15% and that of mine waste soil was 0.4-2.7% (Freeman et al, 1994).…”

Dietary Lead and Phosphate Interactions Affect Oral Bioavailability of Soil Lead in the Mouse

“…Evaluation of Pb RBA estimates obtained in earlier studies in rodents should be examined with respect to dietary P and Ca levels and their molar ratio. For example, earlier studies of soil Pb bioavailability in rats have used both a natural ingredient diet and a purified diet (AIN-76A) with a higher P level. , In analyses reported here, RBA estimates for Pb in NIST SRM 2710a used data obtained from mice that consumed diets with identical P levels. Discordant levels of P in diets which affected the slope of regression lines would affect the calculation of the ratio used to estimate RBA.…”

Bioaccessibility versus Bioavailability of Essential (Cu, Fe, Mn, and Zn) and Toxic (Pb) Elements from Phyto Hyperaccumulator Pistia stratiotes: Potential Risk of Dietary Intake

“…However, according to the current evaluations of the Joint FAO/WHO Expert Committee on Food Additives, there is no safe threshold limit for Pb intake, and even a negligible portion of this toxic metal can produce harmful effects. With regard to Pb absolute bioavailability (ABAV), our findings are consistent with the results of soil-bound Pb ABAV based on bone and liver data . A higher ABAV (approximately 3%) can be estimated on the basis of blood Pb values.…”

In vivo oral bioavailability of Pb sequestered in metal rich granules in bivalves

“…Another approach for estimation of ABA is to compare Pb accumulation in a target organ (normally blood Pb levels) in animals that have been fed Pb-containing food with those subjected to intravenous Pb administration (assumed to be 100% bioavailable). Comparing with intravenous administration of Pb, ABA of Pb-acetate to rats varied depending on the organ considered between 7 and 15% and that of mine waste soil was 0.4-2.7% (Freeman et al, 1994).…”

Dietary Lead and Phosphate Interactions Affect Oral Bioavailability of Soil Lead in the Mouse

“…Evaluation of Pb RBA estimates obtained in earlier studies in rodents should be examined with respect to dietary P and Ca levels and their molar ratio. For example, earlier studies of soil Pb bioavailability in rats have used both a natural ingredient diet and a purified diet (AIN-76A) with a higher P level. , In analyses reported here, RBA estimates for Pb in NIST SRM 2710a used data obtained from mice that consumed diets with identical P levels. Discordant levels of P in diets which affected the slope of regression lines would affect the calculation of the ratio used to estimate RBA.…”