ABO and Rh Blood Groups in Relation to Ovarian, Endometrial and Cervical Cancer Risk Among The Population of South-East Siberia

Yuzhalin, Arseniy E.; Kutikhin, Anton G.

doi:10.7314/apjcp.2012.13.10.5091

Cited by 50 publications

(55 citation statements)

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“…This SNP has a moderate linkage disequilibrium (LD) with rs8176719 (r 2 ¼ 0.57, CHB (Han Chinese in Beijing) population in the 1,000 genome project), an SNP also named the O allele frame-shift mutation affecting amino acid 176. Furthermore, the minor allele of rs633862, suggested the O subgroup, has been found to exert a protective role in ovarian cancer risk in the present study, which is consistent with the findings of previously published studies: A and B subgroups were associated with modestly increased risk of ovarian cancer [38][39][40] .…”

Section: Discussionsupporting

confidence: 82%

Genome-wide association study identifies new susceptibility loci for epithelial ovarian cancer in Han Chinese women

Chen

et al. 2014

Nat Commun

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Ovarian cancer is the leading cause of death from gynaecological malignancies worldwide. Here we perform a three-stage genome-wide association study (GWAS) in Han Chinese women to identify risk genetic variants for epithelial ovarian cancer (EOC). We scan 900,015 single-nucleotide polymorphisms (SNPs) in 1,057 EOC cases and 1,191 controls in stage I, and replicate 41 SNPs (P meta o10 À 4 ) in 960 EOC cases and 1,799 controls (stage II), and an additional 492 EOC cases and 1,004 controls (stage III). Finally, we identify two EOC susceptibility loci at 9q22.33 (rs1413299 in COL15A1, P meta ¼ 1.88 Â 10 À 8 ) and 10p11.21 (rs1192691 near ANKRD30A, P meta ¼ 2.62 Â 10 À 8 ), and two consistently replicated loci at 12q14.2 (rs11175194 in SRGAP1, P meta ¼ 1.14 Â 10 À 7 ) and 9q34.2 (rs633862 near ABO and SURF6, P meta ¼ 8.57 Â 10 À 7 ) (Po0.05 in all three stages). These results may advance our understanding of genetic susceptibility to EOC.

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Section: Discussionsupporting

confidence: 82%

Genome-wide association study identifies new susceptibility loci for epithelial ovarian cancer in Han Chinese women

Chen

et al. 2014

Nat Commun

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“…The results of Kamil et al study, which was conducted on 70 diabetic patients and 140 healthy individuals, showed a negative association between A and O blood types with type II diabetes. Another study by MC Connel et al showed that the relationship between diabetes and group blood A is much more significant and common that diabetes and blood group B. the results of Anderson et al study, also, showed that diabetes was significantly associated with an O group (13). Blood groups, as common important and effective genetic factors, remain constant in many generations and there is a clear and prominent association between various diseases, such as gastric ulcer and gastric cancer and some other diseases, with specific blood types (14).Diabetes mellitus, whose inheritance and zonotypic role are well known, is also a common disease in human societies and it seems that the hypothesis of the association of specific blood groups with this disease seems to be reasonable and backed up, because blood group gene is around 34th band of chromosome numbers 9 and how the blood group affects the interactions of genes seems quite related (15).…”

Section: Discussionsupporting

confidence: 55%

The relationship between blood groups, ABO, and Rh and the risk of diabetes in patients with acute myocardial infarction referring to Amiralmomenin Hospital in Zabol in 2016

2017

Int. J. Adv. Res. Biol. Sci

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Introduction:The main cause of Cardiovascular diseases, especially myocardial infarction, is the arteriosclerosis of coronary arteries. Although the risk factors for arthroplasia are multiple, the risk factors for coronary artery disease are classified into two categories of unmodifiable, such as gender, age and familial history, and modifiable, such as high levels of blood lipids, high blood pressure, smoking, obesity, malaise, stress, emotional exertion, inappropriate diet, taking birth control pills, and diabetes.Diabetes is also the most common disease caused by metabolic disorders..This study was designed to examine the association between diabetes and blood group in patients with acute myocardial infarction. Methodology:The present descriptive cross-sectional study included 116 diabetic patients suffering from acute myocardial infarction admitting to Amiralmomenin Hospital in Zabol. The control group, as well, included 116 patients with non-diabetic acute myocardial infarction admitting to the same hospital.. The collected data was analyzed using SPSS22 and descriptive and chi-square tests. Findings: blood group A was the most common blood group in both groups participating in the present study. There was no significant difference between two groups in terms of distribution of the blood group.In the case group, 104 subjects were Rh positive and 12 were Rh negative and in the control group, 101 subjects were Rh positive and 15 were Rh negative.The difference between two groups was significant in regard with Rh type. Discussion: blood group gene is around 34th band of chromosome numbers 9 and how the blood group affects the interactions of genesseems quite related. All these evidence and many other research findings strongly reinforce the likelihood of association of blood groups with diabetes.

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“…First, our results were based on single-factor estimates without adjustment for other risk factors including age at diagnosis, lifestyle, and other factors. The results from Yuzhalin et al suggested that carriage of non-O blood types increased the risk of ovarian cancer by 40-60%, and the magnitude of this relationship was strongest in women with the AB (IV) blood group (Yuzhalin et al, 2012). And by tackling of obesity epidemic in Arab countries, Ortashi et al indicated that obesity is an important risk factor for endometrial cancer (Ortashi et al, 2013).…”

Section: Discussionmentioning

confidence: 99%

Lack of Associations of the COMT Val158Met Polymorphism with Risk of Endometrial and Ovarian Cancer: a Pooled Analysis of Case-control Studies

Liu

Luo²,

Li³

et al. 2014

Asian Pacific Journal of Cancer Prevention

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Asian Pac J Cancer Prev, 15 (15), 6181-6186 IntroductionOvarian cancer is associated with the highest mortality rate among gynaecological malignancies (Hennessy et al., 2009). There are over 205, 000 new cases and 125, 000 deaths annually from ovarian cancer (Jemal et al., 2011). Endometrial cancer is the fourth most common cancer among women and the most common gynecological cancer in the USA (Jemal et al., 2009). Multiple lines of evidence support a central role of hormones in the etiology of endometrial and ovarian cancers (Lundin et al., 2012). Polymorphisms within genes responsible for estrogen catabolism could alter cellular levels of genotoxic 4-hydroxylated catechol estrogens and antiangiogenic 2-methoxyestradiol, thus influencing risk of developing endometrial and ovarian cancers.Catechol-O-methyltransferase (COMT) catalyzes catechol estrogens to form methyl conjugates, a process that detoxifies the catechol estrogens and prevent them from forming depurinating adducts. In addition, the intermediate products of catechol estrogen metabolism,

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ABO and Rh Blood Groups in Relation to Ovarian, Endometrial and Cervical Cancer Risk Among The Population of South-East Siberia

Cited by 50 publications

References 44 publications

Genome-wide association study identifies new susceptibility loci for epithelial ovarian cancer in Han Chinese women

Genome-wide association study identifies new susceptibility loci for epithelial ovarian cancer in Han Chinese women

The relationship between blood groups, ABO, and Rh and the risk of diabetes in patients with acute myocardial infarction referring to Amiralmomenin Hospital in Zabol in 2016

Lack of Associations of the COMT Val158Met Polymorphism with Risk of Endometrial and Ovarian Cancer: a Pooled Analysis of Case-control Studies

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