1993
DOI: 10.1007/bf00298362
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Abstract: The purpose of this investigation was to test the hypothesis that damage to a lumbar vertebral body can lead to abnormal stress concentrations in the adjacent intervertebral discs. Twenty-three cadaveric lumbar "motion segments", from persons who had died aged between 19 and 87 years, were subjected to substantial compressive loading while in the neutral, lordotic and flexed "postures". During the loading period, a miniature pressure transducer was pulled through the disc along its mid-sagittal diameter and gr… Show more

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Cited by 90 publications
(57 citation statements)
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“…The high frequency of Schmorl's nodes in the lower back is attributed to the anatomy and biomechanics of the lower spine, as the amount of loading on the spine normally increases from the cervical to the lumbar regions (Argoff & Wheeler, 1998). However, back-related trauma is also dependent on posture and various loading factors (Smith, 1969;Chaffin & Park, 1973;Adams et al, 1993). Therefore, the frequency of Schmorl's nodes in the spinal column can vary based on activity patterns and postures.…”
Section: Schmorl's Nodesmentioning
confidence: 97%
“…The high frequency of Schmorl's nodes in the lower back is attributed to the anatomy and biomechanics of the lower spine, as the amount of loading on the spine normally increases from the cervical to the lumbar regions (Argoff & Wheeler, 1998). However, back-related trauma is also dependent on posture and various loading factors (Smith, 1969;Chaffin & Park, 1973;Adams et al, 1993). Therefore, the frequency of Schmorl's nodes in the spinal column can vary based on activity patterns and postures.…”
Section: Schmorl's Nodesmentioning
confidence: 97%
“…Later experiments showed that 'stress' distributions are affected by prior creep loading , by the angulation of adjacent vertebrae (McNally, Adams and Goodship 1993;Adams et al 1994) and by prior damage to the adjacent vertebral bodies .…”
mentioning
confidence: 99%
“…12,13 Data from in vitro studies indicate that endplate injury increases the space available for the nucleus, which cannot increase pressure during flexion, thus decreasing IDP at adjacent segments. 14,21,22 The result of decreased nuclear pressure is increased stress on the annulus and apophyseal ring. 18,23 Tzermiadianos et al 14 tested the hypothesis that the inability of the disk to generate adequate IDP after vertebral fractures in human cadaveric specimens will increase loading of adjacent vertebra predisposing them to fracture even in the absence of a kyphotic deformity.…”
Section: Discussionmentioning
confidence: 99%