“…However, our results correlate with the findings in numerous trials of laparoscopic vs open cholecystectomy showing a significantly greater increase of the IL-6 and CRP levels when open surgery was performed--a finding that is consistent with the greater tissue trauma following taparotomy [1,12,15,20]. Our results regarding postoperative pain and analgesic requirements following the three different surgical procedures are comparable to previously published data [6,10,11,14,17]; however, the number of patients in our series is too smaJl to achieve significant results.…”