Abdominal crisis caused by perforation of ileal lymphoma

Yokota, Takashi; Yamaguchi, Yasuo; Murakami, Yasusuke; Yasuda, Mitsuhiko; Kunii, Yasuo; Yamauchi, Hidemi; Sato, Akihiro; Ishikawa, Izumi

doi:10.1053/ajem.2002.31139

Cited by 5 publications

(6 citation statements)

References 1 publication

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“…A recent study reported free intestinal perforations due to NHL in six patients [5]. As reported in previous studies free intestinal perforations due to NHL may occur both spontaneously and after chemotherapy [11,[16][17][18][19]. In the present study, free intestinal perforation was demonstrated in patients 4 and 7 after chemotherapy.…”

Section: Discussionsupporting

confidence: 85%

Spontaneous Intestinal Perforation Due to Non-Hodgkin's Lymphoma: Evaluation of Eight Cases

et al. 2007

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Primary intestinal lymphoma with spontaneous perforation and after systemic chemotherapy is rare. The present study summarizes retrospectively the outcome of eight free intestinal perforated patients diagnosed with intestinal non-Hodgkin's lymphoma. Two patients had a history of systemic chemotherapy before perforation. The most common symptoms of the patients were abdominal pain, nausea, vomiting, weight loss, and fever. Sites of perforation were ileum in four, jejunum in two, cecum in one, and sigmoid colon in one patient. Synchronous lymphoma was present in three patients. The perforation was closed by primary closure in three patients. Resection/anastomosis was performed in four patients and sigmoid colostomy was performed in one patient. Three patients were lost due to leakage or septicemia. Intestinal lymphoma might be kept in mind as a cause in free intestinal perforations. Because of the high mortality rate early diagnosis and treatment are important to improve the prognosis of bowel perforation in patients with non-Hodgkin's lymphoma.

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Section: Discussionsupporting

confidence: 85%

Spontaneous Intestinal Perforation Due to Non-Hodgkin's Lymphoma: Evaluation of Eight Cases

et al. 2007

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“…The perforation can occur at any point in the gastrointestinal tract including the stomach, jejunum, ileum, and colon. Intestinal perforation due to intestinal lymphoma has been reported by many observers [94,95] as well as PTLD [4,45,96] as with the present case.…”

Section: Life-threatening Complicationssupporting

confidence: 81%

“…Perforated intestinal lymphomas usually are of a higher stage and have a poor prognosis. It was reported that surgery for perforated intestinal lymphomas had high mortality due to sepsis and high reoperation rate [94,95]. Therefore, in transplant patients who require immunosuppressive drugs, especially in patients treated with PSIs which prevent wound healing, jejunostomy or colostomy should be made as with the present case.…”

Section: Life-threatening Complicationsmentioning

confidence: 77%

Posttransplant Lymphoproliferative Disorder after Cardiac Transplantation in Children: Life Threatening Complications Associated with Chemotherapy Combined with Rituximab

Fukushima

2013

ISRN Transplantation

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Despite the excellent long-term survival currently achieved in pediatric heart transplant recipients, posttransplant lymphoproliferative disorders (PTLDs) are one of the most important causes of morbidity and mortality after heart transplantation (HTx), especially in children. Timely and accurate diagnosis based on histological examination of biopsy tissue is essential for early intervention for PTLD. Chemotherapy is indicated for patients with poor response to reduction of immunosuppressive medication and for highly aggressive monomorphic PTLD. The use of rituximab in combination with chemotherapy is effective to suppress B cell type PTLD (B-PTLD). However, PTLD relapses frequently and the outcome is still poor. Although everolimus (EVL) has been reported to inhibit growth of human Epstein-Barr-virus- (EBV-) transformed B lymphocytesin vitroandin vivo, EVL has several side effects, such as delayed wound healing and an increase in bacterial infection. During combined treatment of chemotherapy and rituximab, B-PTLDs are sometimes associated with life-threatening complications, such as intestinal perforation and cardiogenic shock due to cytokine release syndrome. In HTx children especially treated with EVL, stoma should be made to avoid reoperation or sepsis in case of intestinal perforation. In cases with cardiac graft dysfunction possibly due to cytokine release syndrome by chemotherapy with rituximab for PTLD, plasma exchange is effective to restore cardiac function and to rescue the patients.

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“…[12,13] In our study, initial presentation was obstruction due to mass, which caused ileus in 13 patients and perforation in 4 patients. PGI NHL was frequently encountered as single lesion with size of 5.5±3.3 cm (range: 1-13 cm).…”

Section: Discussionmentioning

confidence: 56%

Primary small intestinal non-Hodgkin lymphomas that have been diagnosed after emergency surgery

Avci

Yabanoğlu²,

Arer³

et al. 2016

Ulus Travma Acil Cerrahi Derg

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Abdominal crisis caused by perforation of ileal lymphoma

Cited by 5 publications

References 1 publication

Spontaneous Intestinal Perforation Due to Non-Hodgkin's Lymphoma: Evaluation of Eight Cases

Spontaneous Intestinal Perforation Due to Non-Hodgkin's Lymphoma: Evaluation of Eight Cases

Posttransplant Lymphoproliferative Disorder after Cardiac Transplantation in Children: Life Threatening Complications Associated with Chemotherapy Combined with Rituximab

Primary small intestinal non-Hodgkin lymphomas that have been diagnosed after emergency surgery

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