Abbreviated Combined MR Protocol: A New Faster Strategy for Characterizing Breast Lesions

Moschetta, Marco; Telegrafo, Michele; Rella, Leonarda; Ianora, Amato Antonio Stabile; Angelelli, Giuseppe

doi:10.1016/j.clbc.2016.02.008

Cited by 90 publications

(74 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This result was similar to previously published reports of Kuhl et al (23) and Heacock et al (20), but the interpretation times of AP-1 and AP-2 were shorter than those reported by Moschetta et al (14) and Grimm et al (15). The shorter interpretation times of AP are attributed to the time needed for reading other sequences.…”

Section: Discussionsupporting

confidence: 92%

“…To make breast MRI more accessible for routine screening populations, some investigators have evaluated the benefit of an abbreviated breast MRI protocol. Although the selected sequence of AP was varied, several prior studies demonstrated that an AP of MRI was not only a time-saving tool for radiologists and patients, but also had the same diagnostic potential as FDP of MRI (1314152021). However, to our knowledge, there are no published reports about DWI being used as an abbreviated breast MRI protocol.…”

Section: Discussionmentioning

confidence: 99%

“…Recent studies have evaluated the feasibility of using an abbreviated protocol (AP) of MRI for breast cancer detection (131415), and the results have shown that the AP provided a better detection performance than MG. Therefore, Morris (16) recommended that AP should become a standard protocol for breast cancer screening.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Abbreviated MRI Protocols for Detecting Breast Cancer in Women with Dense Breasts

et al. 2017

View full text Add to dashboard Cite

ObjectiveTo evaluate the validity of two abbreviated protocols (AP) of MRI in breast cancer screening of dense breast tissue.Materials and MethodsThis was a retrospective study in 356 participants with dense breast tissue and negative mammography results. The study was approved by the Nanjing Medical University Ethics Committee. Patients were imaged with a full diagnostic protocol (FDP) of MRI. Two APs (AP-1 consisting of the first post-contrast subtracted [FAST] and maximum-intensity projection [MIP] images, and AP-2 consisting of AP-1 combined with diffusion-weighted imaging [DWI]) and FDP images were analyzed separately, and the sensitivities and specificities of breast cancer detection were calculated.ResultsOf the 356 women, 67 lesions were detected in 67 women (18.8%) by standard MR protocol, and histological examination revealed 14 malignant lesions and 53 benign lesions. The average interpretation time of AP-1 and AP-2 were 37 seconds and 54 seconds, respectively, while the average interpretation time of the FDP was 3 minutes and 25 seconds. The sensitivities of the AP-1, AP-2, and FDP were 92.9, 100, and 100%, respectively, and the specificities of the three MR protocols were 86.5, 95.0, and 96.8%, respectively. There was no significant difference among the three MR protocols in the diagnosis of breast cancer (p > 0.05). However, the specificity of AP-1 was significantly lower than that of AP-2 (p = 0.031) and FDP (p = 0.035), while there was no difference between AP-2 and FDP (p > 0.05).ConclusionThe AP may be efficient in the breast cancer screening of dense breast tissue. FAST and MIP images combined with DWI of MRI are helpful to improve the specificity of breast cancer detection.

show abstract

Section: Discussionsupporting

confidence: 92%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Abbreviated MRI Protocols for Detecting Breast Cancer in Women with Dense Breasts

et al. 2017

View full text Add to dashboard Cite

show abstract

“…It also fits with the findings of Mango et al (12) who were able to demonstrate a high level of sensitivity for detection of cancers with an abbreviated protocol. Moreover, these results are in agreement with the study by Moschetta et al (24) who found that abbreviated protocol has the same diagnostic potential as the standard protocol in patients undergoing breast MRI for screening, problem solving, or preoperative staging. In standard clinical situations, the care provided based on findings from an abbreviated protocol corresponded with what was provided when a standard protocol was used.…”

Section: • January-february 2018 • Diagnostic and Interventional Radisupporting

confidence: 92%

Impact of an abbreviated protocol for breast MRI in diagnostic accuracy

Oldrini¹,

Derraz²,

Salleron³

et al. 2018

Diagn Interv Radiol

View full text Add to dashboard Cite

Breast magnetic resonance imaging (MRI) has a dominant and increasingly important role in breast imaging, particularly for screening of women at high risk of developing breast cancer, staging of breast cancers, follow-up after neoadjuvant chemotherapy, and evaluating axillary lymph nodes when a primary site cannot be found by mammography (1-3). At present, it takes about 30 to 40 minutes to perform a breast MRI in accordance with the good practice guidelines of the European Society of Breast Cancer Specialists (EU-SOMA) (4). This length of time is relatively long, and the examination presents high direct and indirect costs that limit its wider use (5-11).Recently, Kuhl et al. (4) has shown that in high-risk women, the use of an abbreviated protocol is a suitable option that does not compromise the sensitivity or the specificity relative to the conventional complete protocol, thanks to specific characteristics of breast cancers that occur in high-risk women. PURPOSEWe aimed to compare the diagnostic accuracy and interpretation time of an abbreviated protocol relative to the complete protocol of breast magnetic resonance imaging (MRI) with the use of breast imaging reporting and data system (BI-RADS). Between-reader and between-protocol variability for BI-RADS classification and influence of reader expertise on diagnostic accuracies were also evaluated. METHODSWe conducted a retrospective reader study in 90 women who underwent breast MRI: 30 benign examinations (graded as American College of Radiology [ACR] 1 or 2), 30 examinations graded as ACR 3 and 30 examinations requiring a histologic proof (graded as ACR 4 or 5). Two radiologists independently reviewed the protocols. The reference standard was 24 months of imaging follow-up (66.6%, n=60), percutaneous biopsy at the12th month imaging follow-up (5.5%, n=5), and breast surgery (27.9%, n=25). Analysis was done on a per-breast basis. There were 26 cancers in 168 breasts (15.1%) RESULTSInterpretation time was higher for the complete protocol (mean difference: 84 s, 95% CI [67;101] for senior and 83 s, 95% CI [70;95] for junior reader; P < 0.001). The reliability of BI-RADS classification between both protocols was very good with intraclass correlation coefficient of 0.89 for junior reader and 0.98 for senior reader; the inter-reader reliability was 0.94 and 0.90 for the complete and abbreviated protocols, respectively. For senior reader, the abbreviated and complete protocols yielded 95.1% and 94.4% specificity and 100% sensitivity. CONCLUSIONOur data provide corroborating evidence that abbreviated protocols decrease interpretation time without compromising sensitivity or specificity. There was a high level of concordance between the abbreviated and complete protocols and between the two readers.

show abstract

“…52 Since then, additional studies have lent further evidence supporting the abbreviated screening protocols, suggesting that they may replace full protocols in the future without sacrificing diagnostic accuracy. [53][54][55] Another important limitation of MRI is its rate of specificity. The increased sensitivity rate associated with MRI comes at a cost in terms of reduced specificity, thus resulting in increased callback rates and benign findings on biopsies.…”

Section: Magnetic Resonance Imagingmentioning

confidence: 99%

Imaging Management of Breast Density, a Controversial Risk Factor for Breast Cancer

et al. 2017

View full text Add to dashboard Cite

Abbreviated Combined MR Protocol: A New Faster Strategy for Characterizing Breast Lesions

Cited by 90 publications

References 24 publications

Abbreviated MRI Protocols for Detecting Breast Cancer in Women with Dense Breasts

Abbreviated MRI Protocols for Detecting Breast Cancer in Women with Dense Breasts

Impact of an abbreviated protocol for breast MRI in diagnostic accuracy

Imaging Management of Breast Density, a Controversial Risk Factor for Breast Cancer

Contact Info

Product

Resources

About