Abstracts Accepted for Publication 2017
DOI: 10.1136/annrheumdis-2017-eular.6309
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Abstract: BackgroundOsteoimmunology is an evolving field where the multipotential stromal cells (MSCs) can be considered as an important player linking immune response with bone generation. A group of pro-inflammatory cytokines including IFN-γ, TNF-α, IL-17 and IL-1, has been proven to have a licensing effect on MSCs promoting the immunomodulatory activities of MSCs (1). Importantly, these cytokines can regulate the osteogenic differentiation capability of MSCs and in particular, IL-1 and IL-17 can enhance the MSC osteo… Show more

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