PLoS Genet volume 14, issue 8, Pe1007513 2018 DOI: 10.1371/journal.pgen.1007513
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Emily L. Kurdzo, Hoa H. Chuong, Jared M. Evatt, Dean S. Dawson
Abstract:

In meiosis I, homologous chromosomes segregate away from each other–the first of two rounds of chromosome segregation that allow the formation of haploid gametes. In prophase I, homologous partners become joined along their length by the synaptonemal complex (SC) and crossovers form between the homologs to generate links called chiasmata. The chiasmata allow the homologs to act as a single unit, called a bivalent, as the chromosomes attach to the microtubules that will ultimately pull them away from each o…

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