A–Z of nutritional supplements: dietary supplements, sports nutrition foods and ergogenic aids for health and performance: Part 46

Deuster, Patricia A.; Hodgson, Adrian B.; Stear, S J; Burke, Louise M.; Castell, L M

doi:10.1136/bjsports-2013-092699

Cited by 5 publications

(4 citation statements)

References 19 publications

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“…An essential issue to be discussed is that some individuals in the supplemented group reported improvement in sleep quality. This is a very common effect on ZMA users, however not yet investigated by the literature [20] . As the present study also did not evaluate the quality of the individuals' sleep, we cannot assure that ZMA is effective from this purpose.…”

Section: Discussionmentioning

confidence: 99%

ZMA supplementation does not impact IGF-IGFBPs system or body composition of young athletes

Cerqueira¹,

Filho²,

Junior³

et al. 2021

J. Sports Sci. Nutr.

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IGF-IGFBPs system hormones are known for their anabolic role. ZMA is a supplement consisting of zinc, magnesium and vitamin B6, whose premise is to provide an increase in levels of GH, IGF-1 and testosterone. This hypothetical increase could cause significant changes in body composition. However, studies on its effectiveness are divergent in addition do not evaluate the IGF binding proteins (IGFBPs), which are essential in IGF-1 metabolism. Therefore, this study aimed to analyze the effects of ZMA in IGF-1, IGFBP-3 and testosterone levels. Eighteen male amateur athletes were divided into two groups: ZMA and placebo. Hormone levels and anthropometric characteristics were assessed before and after the 8-week intervention. After the intervention, there were no differences between groups in hormonal levels and anthropometric characteristics. Thus, the results suggest that ZMA do not offer any additional benefits for individuals that has an appropriate diet, either in body composition or in hormone levels.

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Section: Discussionmentioning

confidence: 99%

ZMA supplementation does not impact IGF-IGFBPs system or body composition of young athletes

Cerqueira¹,

Filho²,

Junior³

et al. 2021

J. Sports Sci. Nutr.

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“…Recently, the consumption of dietary supplements containing zinc and magnesium, especially among men, became popular due to the belief that this combination could increase testosterone levels and thus promote anabolic effects 36 . These minerals increase insulin-like growth factor (IGF-1) concentrations in children with disabilities; However, this claim has no proven evidence in healthy people 37 , 38 . We found claims in three samples that the combination of zinc, magnesium and vitamin B6, also known as ZMA, contained testosterone precursor substances.…”

Section: Discussionmentioning

confidence: 99%

“…Recentemente, o consumo de suplementos alimentares contendo zinco e magnésio, principalmente entre o sexo masculino, popularizou-se em razão da crença de que essa combinação poderia aumentar os níveis de testosterona e, portanto, promover efeitos anabólicos 36 . Esses minerais são capazes de aumentar as concentrações do hormônio fator de crescimento semelhante à insulina (do inglês insulin-like growth factor, IGF-1) em crianças com deficiência; porém, não há evidências comprovadas para essa alegação em pessoas saudáveis 37 , 38 . A combinação de zinco, magnésio e vitamina B6 é também conhecida como ZMA, e alegações de que essa formulação continha substâncias precursoras da testosterona foram encontradas em três amostras.…”

Section: Discussionunclassified

Regulatory framework for dietary supplements and the public health challenge

et al. 2019

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OBJECTIVE The new regulatory framework for dietary supplements in Brazil prompted this analysis of the current outlook of these products and the challenges posed by the new guidelines.METHODS We conducted a qualitative, observational and descriptive study of dietary supplements commercialized in Brazilian online stores with the help of the Google® search tool. We considered the ingredients on the labels, the effects attributed to these products and the commercial claims used as a means of promoting them to assess the necessary changes for the legal framework in the new guidelines. Finally, with the help of a database, we compared the effects declared by the manufacturers and attributed to certain ingredients with the scientific evidence described in literature.RESULTS In total, we purchased 44 dietary supplements from Brazilian online stores (n = 7). Of the samples studied, 34.2% could not be classified in the category Dietary Supplements, as recommended by the new regulation of the Brazilian Health Regulatory Agency due to the presence of prohibited substances; 16% of products should be commercialized as medicines. Regarding the commercial appeals, 97.7% had banned expressions. Numerous claims of effects attributed to certain products were characterized as consumer fraud because they have no scientific evidence.CONCLUSIONS The necessary changes represent a major regulatory and production challenge due to the wide range of dietary supplements and markets, an effort that aims to protect the consumers’ health. Some previous gaps in the regulatory framework were not fully solved.

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“…This can result in partial sleep restriction (PSR) before an event or training being particularly common. Acute ZMA supplementation (one or two nights) and subsequent sleep and performance in this population has received little attention, with most studies primarily recruiting clinical populations with pre-existing sleep disorders [ 26 ]. As the specific mechanisms of these micronutrients on sleep remain unclear, further work is required given the potential benefits of ZMA for general sleep health and performance.…”

Section: Introductionmentioning

confidence: 99%

Effects of Supplementing Zinc Magnesium Aspartate on Sleep Quality and Submaximal Weightlifting Performance, following Two Consecutive Nights of Partial Sleep Deprivation

Gallagher,

Austin,

Dunlop

et al. 2024

Nutrients

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Purpose: We examined whether supplementation of zinc magnesium aspartate (ZMA), while partially sleep deprived, was beneficial to sleep quality and subsequent morning (07:00 h) submaximal weightlifting. Methods: Using a double-blinded, randomized counterbalanced design, sixteen trained males were recruited and completed six sessions: (i) one repetition max (1 RM) for bench press and back squat; (ii) two familiarisation sessions; (iii) three conditions with 4 h sleep and either: ZMA, placebo (PLA), or NoPill control (NoPill). Submaximal exercise session consisted of three repetitions at 40, 60 and 80% of 1 RM for bench press and back squat. Average power (AP), average velocity (AV), peak velocity (PV), displacement (D) and time-to-peak velocity (tPV) were recorded using MuscleLab linear encoders. Data were analysed using a general linear model with repeated measures and linear correlation. Results: No significant main effect for condition was found for performance values or subjective ratings of fatigue. Main effect for “load” on the bar was found, where AP and tPV values increased with load (p < 0.05). No significant relationship between dose of zinc or magnesium ingested and change in performance for 80% 1 RM power-outputs was found. Conclusion: Supplementation of ZMA for two nights of partial sleep deprivation had no effect on sleep or subsequent morning performance.

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A–Z of nutritional supplements: dietary supplements, sports nutrition foods and ergogenic aids for health and performance: Part 46

Cited by 5 publications

References 19 publications

ZMA supplementation does not impact IGF-IGFBPs system or body composition of young athletes

ZMA supplementation does not impact IGF-IGFBPs system or body composition of young athletes

Regulatory framework for dietary supplements and the public health challenge

Effects of Supplementing Zinc Magnesium Aspartate on Sleep Quality and Submaximal Weightlifting Performance, following Two Consecutive Nights of Partial Sleep Deprivation

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