A Web-Based Study of HIV Prevention in the Era of Pre-Exposure Prophylaxis Among Vulnerable HIV-Negative Gay and Bisexual Men, Transmen, and Transwomen Who Have Sex With Men: Protocol for an Observational Cohort Study

Nash, Denis; Stief, Matthew; MacCrate, Caitlin; Mirzayi, Chloe; Patel, Viraj V.; Hoover, Donald R.; Pantalone, David W.; Golub, Sarit A.; Millett, Gregorio A.; D’Angelo, Alexa B; Westmoreland, Drew; Grov, Christian

doi:10.2196/13715

Cited by 43 publications

(36 citation statements)

References 18 publications

(19 reference statements)

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“…We applied internet-based strategies that have been demonstrated to be effective for recruiting and following large and geographically diverse online cohorts. [2][3][4]…”

Section: Methodsmentioning

confidence: 99%

“…[76] Data will be presented as flat text files (CSV) formatted for compatibility with the New York Times county-level longitudinal case load dataset [3], including date, county, state, and fips code. A GitHub Actions script will perform weekly updates of the repository and its associated GitHub Pages site, automatically incorporating all new submissions from the previous week.…”

Section: Data Sharingmentioning

confidence: 99%

“…1 Internet-based strategies, which facilitate rapid recruitment of large and diverse samples, can be leveraged to understand and inform this swiftly changing and protracted public health crisis. 2,3 In response to the COVID-19 pandemic the CUNY Institute for Implementation Science in Population Health (ISPH) launched the Communities, Households and SARS/COV-2 Epidemiology (CHASING) COVID Cohort "C 3 " study on March 28, 2020. We sought to recruit an online prospective cohort of 7,500 adults (18 years or older) in the United States (US) and US territories in order to rapidly contribute to our understanding of the spread and impact of the SARS/COV2 pandemic within households and communities.…”

Section: Introductionmentioning

confidence: 99%

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Cohort Profile: A national prospective cohort study of SARS-CoV-2 pandemic outcomes in the U.S. - The CHASING COVID Cohort Study

Robertson

Kulkarni

Berry

et al. 2020

Preprint

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Introduction:The Chasing COVID Cohort (C 3 ) study is a US-based, geographically and socio-demographically diverse sample of adults (18 and older) enrolled into a prospective cohort study during the upswing of the U.S. COVID-19 pandemic. Methods:We used internet-based strategies to enroll C 3 participants beginning March 28th, 2020. Following baseline questionnaire completion, study participants will be contacted monthly (for 6 months) to complete assessments of engagement in non-pharmaceutical interventions (e.g., use of cloth masks, avoiding large gatherings); COVID-19 symptoms; SARS/COV2 testing and diagnosis; hospitalizations; healthcare access; and uptake of health messaging. Dried blood spot (DBS) specimens will be collected at the first follow-up assessment (last week of April 2020) and at month 3 (last week of June 2020) and stored until a validated serologic test is available.Results: As of April 20, 2020, the number of people that completed the baseline survey and provided contact information for follow-up was 7,070. Participants resided in all 50 US states, the District of Columbia, Puerto Rico, and Guam. At least 24% of participants were frontline workers (healthcare and other essential workers). Twenty-three percent (23%) were 60+ years, 24% were Black or Hispanic, 52% were men, and 52% were currently employed. Nearly 20% reported recent COVID-like symptoms (cough, fever or shortness of breath) and a high proportion reported engaging in non-pharmaceutical interventions that reduce SARS/COV2 spread (93% avoided groups >20, 58% wore masks; 73% quarantined). More than half (54%) had higher risk for severe COVID-19 illness should they become infected with SARS/COV2 based on age, underlying health conditions (e.g., chronic lung disease), or daily smoking.

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“…We applied internet-based strategies that have been demonstrated to be effective for recruiting and following large and geographically diverse online cohorts. [2][3][4]…”

Section: Methodsmentioning

confidence: 99%

Section: Data Sharingmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Cohort Profile: A national prospective cohort study of SARS-CoV-2 pandemic outcomes in the U.S. - The CHASING COVID Cohort Study

Robertson

Kulkarni

Berry

et al. 2020

Preprint

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“…Data were collected as part of the Together 5000 study—a national, internet-based cohort study of men, trans men and trans women in the United States. 9 10 Enrollment began in October 2017 using ads on men-for-men geosocial sexual networking phone applications and concluded in June 2018. Eligibility criteria for the study are shown in table 1.…”

Section: Methodsmentioning

confidence: 99%

Prior HIV testing behaviour is associated with HIV testing results among men, trans women and trans men who have sex with men in the United States

Grov

Westmoreland²,

Golub

et al. 2020

J Epidemiol Community Health

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BackgroundAmong those at high risk for HIV, it is important to examine the ways in which someone who has recently tested for HIV might differ from someone who has not.MethodsIn 2017–2018, a total of 5001 men, trans women and trans men who have sex with men from across the United States completed an online survey about their recent testing behaviour as well as self-collected oral samples for HIV testing.ResultsIn total, 3.8% tested HIV-positive and—among those with positive results—35% were recent HIV infections (ie, self-reported an HIV-negative test result within the 12 months prior to enrollment). Those with HIV-positive results—regardless of how recent their HIV test was prior to enrollment—differed from those with negative results in ways that are known to be associated with HIV risk: racial and income disparities, housing instability, recent transactional sex and recent methamphetamine use. Among those with HIV-positive results at enrollment, only having a primary care physician distinguished those who recently tested negative prior to enrollment versus not. Among those with HIV-negative results, there were numerous differences between those who had recently tested for HIV prior to enrollment, versus not, such that those who had not recently tested were significantly more likely to report being at higher risk for HIV.ConclusionStrategies aimed at improving more frequent HIV testing among HIV-negative persons at high risk for HIV should address other needs including stable housing, transactional sex, access to a primary care provider and methamphetamine use.

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“…In 2017, the National Institutes of Health funded multiple research sites to conduct Limited Interaction Targeted Epidemiology (LITE) to Advance HIV Prevention [32]. Funded sites are each following thousands of participants through 2022, and at-home HIV testing is an integral component of study participation [32][33][34]. HIV prevention studies operating remotely have the option of using rapid or mail-in HIV testing.…”

Section: Introductionmentioning

confidence: 99%

Experiences Receiving HIV-Positive Results by Phone: Acceptability and Implications for Clinical and Behavioral Research

D’Angelo

Morrison²,

López-Rios

et al. 2020

AIDS Behav

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Improving HIV testing rates and increasing early detection among men who have sex with men (MSM) are critical strategies for enhancing overall health and decreasing HIV transmission. Remote testing and phone delivery of HIV test results may reduce barriers such as geographic isolation or HIV-related stigma. In 2018-19, 50 MSM completed qualitative interviews about their experience receiving a positive HIV test result via phone through their participation in a research study that included remote HIV testing. Interview topics included the acceptability of, and concerns about, phone delivery of HIV results, as well as suggestions for improvement. Interviews were transcribed, coded, and analysed using an inductive thematic approach. Overall, participants reported high acceptability of phone delivery of HIV-positive results. Participants praised the support and information provided by study staff. Benefits identified included increased convenience compared to in-person medical visits, allowing participants to emotionally process their test results privately, as well as receiving the results from supportive and responsive staff members. A few participants indicated drawbacks to phone-based HIV test result delivery, such as logistical concerns about receiving a phone call during the day (e.g., while at work), reduced confidentiality, and the lack of in-person emotional support. Overall, participants described phone delivery of positive HIV-results as acceptable. At-home testing with phone delivery has the potential to increase HIV testing access, especially to geographically isolated or medically underserved patients.

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A Web-Based Study of HIV Prevention in the Era of Pre-Exposure Prophylaxis Among Vulnerable HIV-Negative Gay and Bisexual Men, Transmen, and Transwomen Who Have Sex With Men: Protocol for an Observational Cohort Study

Cited by 43 publications

References 18 publications

Cohort Profile: A national prospective cohort study of SARS-CoV-2 pandemic outcomes in the U.S. - The CHASING COVID Cohort Study

Cohort Profile: A national prospective cohort study of SARS-CoV-2 pandemic outcomes in the U.S. - The CHASING COVID Cohort Study

Prior HIV testing behaviour is associated with HIV testing results among men, trans women and trans men who have sex with men in the United States

Experiences Receiving HIV-Positive Results by Phone: Acceptability and Implications for Clinical and Behavioral Research

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