A water-soluble metal–organic complex array as a multinuclear heterometallic peptide amphiphile that shows unconventional anion dependency in its self-assembly

Abstract

Water-soluble metal–organic complex array 1, bearing Ru(ii), Pt(ii) and Rh(iii) complexes at the side residues of the short peptide, exhibits anion and pH-responsive self-assembling behaviours in aqueous media.

Light induced construction of porous covalent organic polymeric networks for significant enhancement of CO2 gas sorption

“…Precise molecular self-assembly enables the arrangement of molecules in a well-dened molecular architecture with specic shape and size. The controlled self-assembly of peptide-based amphiphiles has attracted great attention due to their unique architectures, including bers, [20][21][22][23][24] tubes, [25][26][27] spheres, [28][29][30][31] vesicles [32][33][34][35] and cylinders [36][37][38] as well as their applications in drug delivery 39,40 and injectable therapy to control hemorrhage. 41 Peptide-based bolaamphiphiles are a unique class of amphiphiles, which can self-assemble into different architectures through noncovalent interactions upon the inuence of external stimuli.…”

Sequence-Specific Detection of Unlabeled Nucleic Acid Biomarkers Using a “One-Pot” 3D Molecular Sensor

“…Functional groups are evenly spaced throughout the fibrous structure due to the stochastic nature of self-assembly. 34 We find here that the ability to increase spatial separation between probes on the fiber surface minimizes unwanted probe–probe interactions, which may cause the poor sensitivity or false positives suffered by 2D microarray and biosensor devices. Functional hydrogel materials also have greater storage capacity than 2D systems, 35,36 which here improves the detection limits and sensitivity.…”

A Glutathione‐Responsive Short Sequence of Metal–Organic Complex Array

“…Because previously reported MOCAs need help from polar organic solvents to dissolve in buffered media, we modified the sequence by replacing Glu with Arg to increase solubility in these media. Coupling of Ru monomer, Arg, Pt monomer, Arg, and tri(ethylene glycol) acid, in this order, and cleavage of the resultant species from the resin afforded a crude mixture containing 1 Cl .…”