A water-soluble AIE-gen for organic-solvent-free detection and wash-free imaging of Al³⁺ ions and subsequent sensing of F⁻ ions and DNA tracking

Abstract

A water-soluble TPE-based AIEgen (TPE-diBuS) was developed for organic-solvent-free detection of Al3+ ions and its wash-free cell imaging. The TPE-diBuS-Al ensemble was used for the detection of F− ions and DNA tracking.

A sensitive OFF–ON–OFF fluorescent probe for the cascade sensing of Al3+ and F− ions in aqueous media and living cells

“…[21][22][23] Interestingly, emissive probe + Al 3+ complexes can serve as anion sensors, especially to F À . [24][25][26][27][28][29] And these sensors that are capable of detecting Al 3+ and F À sequentially by uorescence OFF-ON-OFF signaling response are highly effective when compared with the one-to-one probes. [30][31][32] With these considerations in mind, we herein report an easily synthesizable Schiff base receptor 2-hydroxy-1naphthaldehyde semicarbazone (HNS), which commendably supports the idea of the sequential sensing property for Al 3+ and F À in aqueous media and live cells.…”

Recent Advances in Aggregation-Induced Emission Chemosensors for Anion Sensing

“…On the contrary, water-soluble TPE derivative A12 readily formed blue-emissive insoluble aggregates in the presence of Al 3+ based on ionic interactions. The addition of fluoride, however, induced disaggregation and hence an emission turn-off due to the preferential formation of AlF 3 [53]. Organic supramolecular gelator A13 exhibited different fluorescence responses upon gelating in the presence of Zn 2+ and fluoride.…”

Phthalimide conjugation turns the AIE-active tetraphenylethylene unit non-emissive: its use in turn-on sensing of hydrazine in solution and the solid- and vapour-phase

“…In the last few years, mechanochemical synthesis of organic compounds has become one of the emerging methods because it is a high yielding, energy-efficient, economic, and environmental friendly protocol that can avoid harsh conditions, use of volatile organic solvents etc. 45,46 In recent years, our research efforts are directed towards designing and synthesizing uorimetric sensors [47][48][49][50][51] for environmentally and biologically important analytes particularly by environmentally benign ways [49][50][51] including mechanochemistry. 51 Herein, we report a non-emissive new AIEgen, tetraphenylethylene phthalimide (TPE-PMI), by the simple condensation of TPE-NH 2 with phthalic anhydride using solvent-free mechanochemical condition and used for the selective and sensitive detection of hydrazine using AIE-phenomenon.…”