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Cited by 120 publications
(26 citation statements)
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“…The group B coxsackieviruses (CVBs) (serotypes 1 to 6) were discovered in the 1950s in a search for new poliovirus-like viruses (33,61). Infections caused by CVBs are often asymptomatic but may occasionally result in severe diseases of the heart, pancreas, and central nervous system (99).…”
mentioning
confidence: 99%
“…The group B coxsackieviruses (CVBs) (serotypes 1 to 6) were discovered in the 1950s in a search for new poliovirus-like viruses (33,61). Infections caused by CVBs are often asymptomatic but may occasionally result in severe diseases of the heart, pancreas, and central nervous system (99).…”
mentioning
confidence: 99%
“…Furthermore, 9 patients who failed to develop neutralizing antibodies also had no complement-fixing antibodies. DISCUSSION Evidence which has been accumulating in this as well as in other laboratories (1)(2)(3)9) indicates that infection with C virus is not only present in many areas of this country, but that it may actually have accounted for an appreciable, though unknown, proportion of cases of mild illnesses (and perhaps severe ones as well) in 1947 and 1948. The evidence for this occurring in Ohio in 1947 is furnished by the data in this paper: (a) the isolation of 3 related strains from 8 patients examined,* and (b) the serological evidence of an increase in both neutralizing and complement-fixing antibodies in these 3 patients as well as in 4 of 10 others.…”
Section: /8(2)mentioning
confidence: 99%
“…As reported earlier (2), one of the sources from which the C virus was isolated included specimens of feces collected in Akron, Ohio, in 1947. A pool of fecal samples collected from 6 hospitalized patients with a diagnosis of nonparalytic poliomyelitis was found to contain both poliomyelitis virus and C virus.…”
mentioning
confidence: 99%
“…Coxsackievirus was first discovered as a filterable agent associated with a paralytic syndrome, so named for its identification in Coxsackie, New York (coxsackievirus type A) (Dalldorf and Sickles, 1948). Coxsackievirus type B (CVB) was isolated the following year from patients with aseptic meningitis and by the mid-1950s an association with acute myocarditis in humans was apparent (Melnick et al, 1949). Many other viruses have since been shown to cause myocarditis and its long term sequelae, arrhythmias, dilated cardiomyopathy (DCM) and heart failure.…”
Section: Introductionmentioning
confidence: 99%