A vinyl sulfone clicked carbon dot-engineered microfluidic paper-based analytical device for fluorometric determination of biothiols

Carbon Dots in Bioimaging, Biosensing and Therapeutics: A Comprehensive Review

“…Reproduced with permission. [ 171 ] Copyright 2020, Springer. d) CDs detection of DNF by a ratiometric fluorescence shift mechanism.…”

“…[ 170 ] Moreover, since iodine can undergo a substitution reaction with biological thiols, CDs modified with iodine can be used for the fluorescence turn‐on measurement of biological thiols (GSH, Cys, and Hcy) (Figure 5c). [ 171 ] For the second strategy, nanomaterials such as layered transition‐metal oxides or disulphides (e.g., MnO 2 and MoS 2 ), graphene oxide (GO) and metal nanoparticles (NPs) (e.g., Ag and Au NPs) are generally utilized as quenchers. On this basis, the addition of analytes releases CDs from the nanomaterials enabling fluorescence recovery.…”

“…c) CDs detection of amino acids by an off-on mechanism. Reproduced with permission [171]. Copyright 2020, Springer.…”

Review on Carbon Dot-Based Fluorescent Detection of Biothiols

“…The CDs-based fluorescent biothiols assay was illustrated by (1) the CD–metal ion pair system [ 87 , 88 , 89 , 90 , 91 , 92 , 93 , 94 , 95 , 96 , 97 , 98 , 99 , 100 , 101 , 102 , 103 , 104 , 105 , 106 , 107 , 108 , 109 , 110 , 111 , 112 , 113 , 114 , 115 , 116 , 117 , 118 , 119 , 120 , 121 , 122 , 123 , 124 ] and (2) CD-nanocomposites [ 125 , 126 , 127 , 128 , 129 , 130 , 131 , 132 , 133 , 134 , 135 , 136 , 137 , 138 , 139 ,…”

“…In general, CD–nanocomposites produced by compositing inorganic nanomaterials (such as Au NPs, Ag NPs, and MnO 2 , etc.) and few organic molecule functionalized composite models [ 125 , 126 , 127 , 128 , 129 , 133 , 134 , 135 , 136 , 137 , 138 , 139 , 140 , 141 ] follows the reaction-based mechanism-2 ( Figure 3 B). On the other hand, few organic moiety functionalized CD–nanocomposite models [ 142 , 143 , 144 ] follows the reaction-based mechanism-1 ( Figure 3 A).…”