A “Turn-On” fluorescent chemosensor with the aggregation-induced emission characteristic for high-sensitive detection of Ce ion

Aggregation‐Induced Emission of Multiphenyl‐Substituted 1,3‐Butadiene Derivatives: Synthesis, Properties and Application

“…The fluorescencei ntensity of TPB-6a aggregates increased linearly with the concentration of Ce(NO 3 ) 3 from 0t o1 8mmol L À1 (R 2 = 0.995) with ad etection limit of 2.27 mmol L À1 , [76] as shown in Figure 7A.W hen the concentration of Ce 3 + was higher than 20 mmol L À1 ,t he fluorescencei ntensities remained almostc onstant. Therefore, the molar ratio of TPB-6a to Ce 3 + was approximately 1:2, indicating that each carboxyl group on TPB-6a coordinated to only one Ce 3 + .F urthermore, the emission maximum gradually shifted from 470 to 500 nm when the concentration of Ce 3 + increased from 0t o2 0mmol L À1 .T his suggests that the presenceo fC e 3 + further enhanced the aggregation of TPB-6a, causing the molecular conformation to be more restricteda nd the conjugation to be extended and thus leading to the redshift in the fluorescence maxima of TPB-6a.…”

“…Moreover,T PB-6a showed good selectivity for Ce 3 + in the presence . [76,77] of other competitive ions such as Al 3 + ,B a 2 + ,C a 2 + , Cd 2 + ,A g + ,C r 3 + ,and Hg 2 + ,ass hown in Figure 7B. Hg 2 + ions could light up HPB-4b and enhancei ts PL intensity.…”

“…The fluorescence intensity of TPB‐6a aggregates increased linearly with the concentration of Ce(NO 3 ) 3 from 0 to 18 μmol L −1 (R 2 =0.995) with a detection limit of 2.27 μmol L −1 , as shown in Figure A. When the concentration of Ce 3+ was higher than 20 μmol L −1 , the fluorescence intensities remained almost constant.…”

“…Inset: PL spectra in the presence of different amounts of Hg 2+ ([HPB‐4b]=10 μmol L −1 in a mixture of THF:H 2 O=1:9 as solvent). (D) Fluorescence response of HPB‐4b (10 μmol L −1 , THF:H 2 O=1:9) upon the addition of different metal ions (6.67 μmol L −1 ) (a: Cd 2+ , b: K + c: Ba 2+ , d: Ca 2+ , e: Zn 2+ , f: Mg 2+ , g: Cd 2+ , h: Al 3+ , i: Cr 3+ , j: Ce 3+ , k: Na + , l: Pb 2+ , m: Fe 2+ , n: Hg 2+ , o: Ag + ) …”

A Freezing‐Induced Turn‐On Imaging Modality for Real‐Time Monitoring of Cancer Cells in Cryosurgery

“…[8] Theb leaching of traditional organic dyes is another issue.I nterestingly,t he aggregation-induced emission (AIE) fluorogens show strong fluorescence in aggregated states owing to the restriction of intramolecular rotations. [9] In this work, we report, for the first time,t he synthesis and utilization of an AIE fluorogen (TABD-Py) for the real-time imaging of cancer cells upon freezing.O wing to their specific interaction with ice crystals as well as their enrichment mostly inside the cancer cells, TABD-Py molecules aggregate specifically inside the cancer cells upon freezing,d isplaying turn-on fluorescence upon freezing.W es how that the high fluorescence intensity upon freezing,h igh sensitivity to ice formation, high specificity to cancer cells,a nd the great biocompatibility make this AIE fluorogen as uperior agent for real-time imaging-based guidance during the cryosurgery. Figure 1ashows the molecular structure of TABD-Py (the detailed synthetic route is shown in Scheme S1 in the Supporting Information).…”