A trial of goal- oriented hemodynamic therapy in critically ill patients

Acute Kidney Injury In Children Admitted In Pediatric Intensive Care Unit

“…Our finding is supported by similar data by others (12). Although the role of renal hypoperfusion is believed to contribute to the development of renal dysfunction, AKI appears to be only partially reversible after optimization of systemic hemodynamics (34).…”

Acute Kidney Injury In Children Admitted In Pediatric Intensive Care Unit

“…Our finding is supported by similar data by others (12). Although the role of renal hypoperfusion is believed to contribute to the development of renal dysfunction, AKI appears to be only partially reversible after optimization of systemic hemodynamics (34).…”

Incidence of low central venous oxygen saturation during unplanned admissions in a multidisciplinary intensive care unit: an observational study

“…Nevertheless, the LOS before ICU did not correlate with the admission ScvO 2 . The ScvO 2 values at admission in our study were comparable to the SvO 2 values reported by Gattinoni and coworkers [ 25 ] for septic patients.…”

Potential Interventions in Sepsis-Related Acute Kidney Injury

“…The importance of early goal-directed therapy is supported by work done by Rivers et al (28), who, in a single-center study, demonstrated that early versus delayed administration of fluid, vasopressors, blood products, and inotropes to maintain central venous oxygen saturation of Ͼ70% had important benefits in terms of mortality and multiorgan failure. This is in contrast to an earlier study (29) in which therapies directed to maintenance of a target cardiac index or mixed venous oxygen saturation in patients with established sepsis did not improve outcome. These observations highlight the importance of early initiation of resuscitation.…”

Acute Kidney Injury In Children Admitted In Pediatric Intensive Care Unit

“…Our finding is supported by similar data by others (12). Although the role of renal hypoperfusion is believed to contribute to the development of renal dysfunction, AKI appears to be only partially reversible after optimization of systemic hemodynamics (34).…”

Incidence of low central venous oxygen saturation during unplanned admissions in a multidisciplinary intensive care unit: an observational study

“…Nevertheless, the LOS before ICU did not correlate with the admission ScvO 2 . The ScvO 2 values at admission in our study were comparable to the SvO 2 values reported by Gattinoni and coworkers [ 25 ] for septic patients.…”

Potential Interventions in Sepsis-Related Acute Kidney Injury

“…The importance of early goal-directed therapy is supported by work done by Rivers et al (28), who, in a single-center study, demonstrated that early versus delayed administration of fluid, vasopressors, blood products, and inotropes to maintain central venous oxygen saturation of Ͼ70% had important benefits in terms of mortality and multiorgan failure. This is in contrast to an earlier study (29) in which therapies directed to maintenance of a target cardiac index or mixed venous oxygen saturation in patients with established sepsis did not improve outcome. These observations highlight the importance of early initiation of resuscitation.…”

Acute Kidney Injury In Children Admitted In Pediatric Intensive Care Unit

“…Our finding is supported by similar data by others (12). Although the role of renal hypoperfusion is believed to contribute to the development of renal dysfunction, AKI appears to be only partially reversible after optimization of systemic hemodynamics (34).…”

Incidence of low central venous oxygen saturation during unplanned admissions in a multidisciplinary intensive care unit: an observational study

“…Nevertheless, the LOS before ICU did not correlate with the admission ScvO 2 . The ScvO 2 values at admission in our study were comparable to the SvO 2 values reported by Gattinoni and coworkers [ 25 ] for septic patients.…”

Potential Interventions in Sepsis-Related Acute Kidney Injury

“…The importance of early goal-directed therapy is supported by work done by Rivers et al (28), who, in a single-center study, demonstrated that early versus delayed administration of fluid, vasopressors, blood products, and inotropes to maintain central venous oxygen saturation of Ͼ70% had important benefits in terms of mortality and multiorgan failure. This is in contrast to an earlier study (29) in which therapies directed to maintenance of a target cardiac index or mixed venous oxygen saturation in patients with established sepsis did not improve outcome. These observations highlight the importance of early initiation of resuscitation.…”