A transcriptome-wide association study identified susceptibility genes for hepatocellular carcinoma in East Asia
Jingjing Zhang,
Qingrong Zhang,
Wenyan Hu
et al.
Abstract:Background
Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide and is prevalent in East Asia. Although genome-wide association studies (GWASs) of HCC have identified 23 risk regions, the susceptibility genes underlying these associations largely remain unclear. To identify novel candidate genes for HCC, we conducted liver single-tissue and cross-tissue transcriptome-wide association studies (TWASs) in two populations of East Asia.
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