A systematic review of the evidence on spontaneous resolution of laryngomalacia and its symptoms

Isaac, André; Zhang, Han; Soon, Sue Rene; Campbell, Sandy; El‐Hakim, Hamdy

doi:10.1016/j.ijporl.2016.01.028

Cited by 30 publications

(17 citation statements)

References 22 publications

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“…A recent systematic review addressing the natural history in otherwise healthy infants could only identify 3 papers (411 patients), all retrospective, which met the study inclusion criteria 16 . Eighty-nine per cent of cases ‘resolved’ (i.e.…”

Section: Discussionmentioning

confidence: 99%

Laryngomalacia: is there an evidence base for management?

2017

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Section: Discussionmentioning

confidence: 99%

Laryngomalacia: is there an evidence base for management?

2017

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“…We have confirmed what was suggested in prior studies regarding the clinical course and management of LM. 3,7 The vast majority of patients did not need medical or surgical therapy and could simply be observed clinically. A high percentage were started on anti-acid therapy with improved symptoms.…”

Section: Demographics Characteristics N (%)mentioning

confidence: 99%

“…L aryngomalacia (LM) is defined as collapse of upper larynx during inhalation. 1 It is the most common cause of stridor in newborns [2][3][4] affecting 45-75% of all infants with congenital stridor. 5 The range of disease presentation, progression, and outcomes varies.…”

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confidence: 99%

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Correlation between the clinical severity of laryngomalacia and endoscopic findings

Alshumrani

Matt

Daftary

et al. 2020

SMJ

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‫املرضى‬ ‫كان‬ .)p=0.0220(‫معتدل‬ ‫بشكل‬ LM‫و‬)p=0.0214(‫بسيط‬ ‫بشكل‬ ‫وعندما‬ ،)p=0.0051(‫الثالث‬ ‫النوع‬ ‫من‬ ‫بكثير‬ ‫‪LM‬أكبر‬ ‫من‬ ‫األول‬ ‫بالنوع‬ ‫املصابني‬ ‫كانت‬ ‫السريرية،‬ ‫والشدة‬)PSG(‫النوم‬ ‫مخطط‬ ‫متغيرات‬ ‫بني‬ ‫االرتباطات‬ ‫اختبار‬ ‫مت‬ ‫التنفسي‬ ‫النفس‬ ‫انقطاع‬ ‫مؤشر‬ ‫كان‬ .PSG ‫في‬ ‫العمر‬ ‫مع‬ ‫مهمة‬ ‫ارتباطات‬ ‫هناك‬ ‫بكثير‬ ‫أقل‬)p=0.0242(‫واملعتدل‬)p=0.0103(‫البسيط‬ ‫في‬)AHI(‫العام‬ ‫بكثير‬ ‫أقل‬ REM(AHI(‫السريعة‬ ‫العني‬ ‫حركة‬ ‫كانت‬ ‫الشديدة.‬ ‫املجموعة‬ ‫من‬ ‫بشكل‬ ‫أقل‬)EtCO 2 (‫كان‬ .)p=0.0134(‫شديدة‬ ‫من‬ ‫املعتدلة‬ ‫احلاالت‬ ‫في‬ ‫إجمالي‬ .)p=0.0141(‫الشديدة‬ ‫باحلدة‬ ‫مقارنة‬ ‫اخلفيفة‬ ‫احلاالت‬ ‫في‬ ‫ملحوظ‬ ‫يحدث‬ SpO 2 ()TST(90%(‫النوم‬ ‫وقت‬ ‫احمليطي‬ ‫الشعري‬ ‫األكسجني‬ ‫تشبع‬ ‫من‬ ‫بكثير‬ ‫أقل‬)p=0.0498(‫واملعتدل‬)p=0.0197(‫اخلفيف‬ ‫من‬ ‫كل‬ ‫في‬ ‫الشديدة.‬ ‫املجموعة‬ ‫الداخلي‬ ‫التنظير‬ ‫أنواع‬ ‫مع‬ LM ‫ـ‬ ‫ل‬ ‫السريرية‬ ‫املظاهر‬ ‫شدة‬ ‫ترتبط‬ ‫لم‬ ‫اخلالصة:‬ ‫العني‬ ‫حركة‬ ‫بقيت‬ .LM ‫الثالث‬ ‫النوع‬ ‫مع‬ ‫زرقة‬ ‫وجود‬ ‫ارتبط‬ ‫دراستنا.‬ ‫في‬ ‫املختلفة‬ ‫السريرية.‬ ‫باحلدة‬ ‫كبير‬ ‫بشكل‬ ‫مرتبطة‬ ‫النوم‬ ‫مخطط‬ ‫في‬ EtCO 2 ‫و‬ AHI ‫السريعة‬ Objectives: To correlate the clinical severity of laryngomalacia (LM) with endoscopic findings, swallowing evaluations and polysomnography in a cohort of patients. Methods: We conducted a retrospective analysis between 2017-2018 on a cohort of patients diagnosed with upper airway obstruction (UAO), stridor, noisy breathing or laryngomalacia.

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“…40%-ban a betegség közepesen súlyos tünetekkel jár, amelyek alvási apnoét, táplálási nehezítettséget okoznak. Az esetek 20%-ában a laryngomalacia súlyos fokú, kifejezett dyspnoe és táplálási képtelenség miatt sebészileg kell beavatkozni [3,4]. Az 1980-as évekig a sebészeti megoldás egyet jelentett a tracheotomiával, amelyet mára az igen magas fokú morbiditás, illetve a gyermek és családja számára megterhelő kanülviselés miatt elkerülünk.…”

Section: Eredeti Közleményunclassified