A systematic review of health state utility values in Thai cancer patients

Kangwanrattanakul, Krittaphas

doi:10.1080/14737167.2022.2123796

Cited by 1 publication

(1 citation statement)

References 64 publications

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“…The EQ-5D-5L has been proven to be a practical, reliable, and valid instrument, with better discriminatory power than the EQ-5D-3L in the general population [ 3 ] and in therapeutic settings [ 36 , 37 ]. However, both versions have been used to generate HU scores in patients with chronic diseases, especially for cancer patients [ 38 ], because both versions have a Thai-specific value set to compute the HU scores [ 39 , 40 ]. As a result, there is clear need to establish population norms for the EQ-5D-3L and EQ-5D-5Lto benchmark the HU scores for evaluating population health care, health equity, and health care interventions among the Thai population.…”

Section: Introductionmentioning

confidence: 99%

EQ-5D-3L and EQ-5D-5L population norms for Thailand

Kangwanrattanakul,

Krägeloh

2024

BMC Public Health

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Background The previous Thai norm-based scores for the EQ-5D-5L were established with Thai general population samples aged 20–70 years in 2019. Nevertheless, these values need to be updated after the COVID-19 pandemic because of its effects on both physical and mental health. This study therefore aimed to establish population norms of the Thai EQ-5D-3L, EQ-5D-5L and EQ-VAS scores as well as to estimate disutility values associated with self-reported main diseases. Methods Individual face-to-face interviews were conducted with 2000 adult (age ≥ 18 years) members of the general Thai population to estimate norm-based scores. Each participant completed the EQ-5D-3L and EQ-5D-5L as well as questions related to their sociodemographic factors and self-reported main diseases. Responses to the two instruments were converted to health utility (HU) scores on the basis of available value sets. Descriptive statistics were used to report the norm-based scores stratified by age and sex categories. Response redistribution determining the response consistency between EQ-5D versions was investigated. The HU score agreement from those two instruments was investigated using intraclass correlation coefficient (ICC). Tobit regression models were employed to investigate the relationships between sociodemographic factors and HU and EQ-VAS scores. Moreover, it was used to estimate the disutility values associated with self-reported main diseases. Results The means (percentage of ceiling effects) of EQ-5D-3L, EQ-5D-5L, and EQ-VAS scores were 0.845 (57.80%), 0.923 (49.05%), and 79.83 (3.20%), respectively. The average percentage of inconsistent response was 1.09%. A good agreement level was found between both EQ-5D versions with the ICCs of 0.789 (95% CI: 0.558–0.878). Female, older, and unemployed participants and those with BMI ≥ 30 reported lower EQ-5D-3L and EQ-5D-5L than their counterparts. Bone/Joint disorder and stroke contributed to the largest disutility value for those two instruments. Conclusions The Thai norm-based scores from those two instruments were diminished when advancing age and among female, unemployed, and obese (BMI ≥ 30) participants. It is expected to provide information to policy makers to better allocate health care resources to those with diminished norm-based scores.

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