A systematic review of Bell’s Palsy as the only major neurological manifestation in COVID-19 patients

Gupta, Sonia; Jawanda, Manveen Kaur; Taneja, Neeraj; Taneja, Tannu

doi:10.1016/j.jocn.2021.06.016

Cited by 33 publications

(43 citation statements)

References 24 publications

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“…COVID-19-related pediatric cases appear to have a milder course of disease. Nevertheless, an increasing number of cases of acute idiopathic paralysis of the facial nerve has been reported, which are usually the first symptoms to appear or occur during the acute phase within the first week of viral symptoms onset [ 10 ]. However, it is important to take this manifestation into consideration also a few weeks after the acute phase, when serology is positive and the nasopharyngeal swab is negative.…”

Section: Discussionmentioning

confidence: 99%

“…The treatment includes steroids and supportive care (eye lubricant); antiviral therapy has shown effective results in the acute management of adults and in one pediatric case [ 10 , 11 , 15 ].…”

Section: Discussionmentioning

confidence: 99%

“…Literature has reported 8 children with peripheral facial nerve palsy associated with COVID-19- All children received oral steroid therapy. In one case, intravenous acyclovir was administered as the child had hyper IgM syndrome and was in the acute phase of the disease (nasopharyngeal swab positive) [ 1 , 3 , 10 , 15 ].…”

Section: Discussionmentioning

confidence: 99%

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A case of facial nerve palsy in a pediatric patient associated with Covid-19

et al. 2022

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Background Pediatric facial nerve palsy is acute and mostly idiopathic; other causes are post-infectious forms. Case presentation We describe a rare case of facial nerve palsy associated with COVID-19 in a 5-year-old boy. The diagnosis of post-infectious COVID-19-related facial paralysis was made by serology positivity for a previous infection (IgG positive, IgM and IgA weakly positive), in the presence of a negative molecular nasopharyngeal swab and in the absence of other etiologies. Early treatment with steroids (1 mg/day for 7 days followed by tapering) and supportive care solved the problem. Conclusion In a child with facial paralysis, COVID-19 must be considered as the cause and both nasopharyngeal swab and serology must be performed.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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A case of facial nerve palsy in a pediatric patient associated with Covid-19

et al. 2022

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“…We have reported one case of facial paralysis. This is relevant since current literature suggests that facial paralysis might be the only or the first finding of COVID-19 [ 12 , 13 , 26 , 27 ]. Egilmez et al found in their study that most patients with facial paralysis have a grade 4 on House-Brackmann scale at first admission, and after 2-5 weeks of steroid treatment 37.5% recovered [ 27 ].…”

Section: Discussionmentioning

confidence: 99%

In Search of a Neurotologic Profile in COVID-19 — A Study in Health Care Workers

Espinoza-Valdez¹,

Celis‐Aguilar²,

Torres-Gerardo³

et al. 2022

Cureus

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Introduction COVID-19 is an emerging disease and the neurotologic symptoms are still not well understood. Furthermore, the development of a neurotological profile and its associated factors can help the clinician in the diagnosis and treatment of this disease. The objective is to determine the neurotologic manifestations experienced by COVID-19 positive health care workers and their associated factors. Methods A symptoms survey was administered to health care workers who were positive to COVID-19 from September to October 2020. An informed consent form was digitally signed and Google Forms software was used for the survey. Frequencies and percentages were used for categorical variables, and associated clinical features were reported with odds ratios. Results We included 209 COVID-19 positive health care workers, 55.5% (n = 116) were women, and 44.5% (n = 93) were men. Fifty-three percent of patients were 20 to 30 years old and 56.4% had at least one comorbidity. The prevalence of neurotological manifestations was 18.6% (n = 39/209), the most frequent symptoms were vertigo (61.5%, n = 24/39), tinnitus (43.5%, n = 17/39), imbalance (43.5%, n = 17/39), and one case of facial paralysis (2.5%, n = 1/39). Neurotological manifestations were associated predominantly with asthenia ( p = 0.021), loss of smell ( p = 0.002) and taste dysfunction ( p = 0.002). Conclusion The most common neurotological manifestations were vertigo, tinnitus and imbalance. Clinical features associated with a neurotologic profile were asthenia, hyposmia and dysgeusia.

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“…Within the spectrum of inflammatory neuropathies, COVID-19 infections have also been hypothesized to provoke cranial nerve problems, most prominently affecting the olfactory nerve causing anosmia. Other prominent associations of COVID-19 infections include facial nerve palsy [78] . In one large case series, cranial nerve deficits were found in over 40% of the 300 or so patients examined, with many patients demonstrating multi-cranial nerve impairments along the spectrum of polycranialis neuritis [79] .…”

Section: Neurologic Manifestationsmentioning

confidence: 99%