2020
DOI: 10.1002/jmv.26398
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Abstract: Objective To provide a comprehensive and systematic analysis of demographic characteristics, clinical symptoms, laboratory findings and imaging features of coronavirus disease 2019 (COVID‐19) in pediatric patients. Methods A meta‐analysis was carried out to identify studies on COVID‐19 from December 25, 2019 to April 30, 2020. Results A total of 48 studies with 5829 pediatric patients were included. Children at all ages were at risk for COVID… Show more

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Cited by 273 publications
(276 citation statements)
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“…Few studies addressed differences in symptom profiles by age among CYP. A large high-quality review by Cui et al 15 reported that proportions with fever and cough were similar in infants to those in older children, conclusions supported by a small lowquality review by Yasuhara et al 13 In contrast, in a small medium-quality review, Christophers et al 20 reported that fever appeared more common in older children (65%) than in infants (48%). Christophers et al 20 also reported that vomiting and diarrhoea occurred largely in those under 9 years, whereas Yasuhara et al 13 reported gastrointestinal symptoms to be more common in adolescents, although numbers were small and symptoms uncommon in all ages.…”
Section: Resultsmentioning
confidence: 98%
See 1 more Smart Citation
“…Few studies addressed differences in symptom profiles by age among CYP. A large high-quality review by Cui et al 15 reported that proportions with fever and cough were similar in infants to those in older children, conclusions supported by a small lowquality review by Yasuhara et al 13 In contrast, in a small medium-quality review, Christophers et al 20 reported that fever appeared more common in older children (65%) than in infants (48%). Christophers et al 20 also reported that vomiting and diarrhoea occurred largely in those under 9 years, whereas Yasuhara et al 13 reported gastrointestinal symptoms to be more common in adolescents, although numbers were small and symptoms uncommon in all ages.…”
Section: Resultsmentioning
confidence: 98%
“…We included 18 reviews in our analysis. [11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28] Characteristics of the included reviews are shown in table 1; all are freely available online (see online supplemental appendix table 2). All reviews were in English.…”
Section: Resultsmentioning
confidence: 99%
“…As a direct consequence, most countries have decided to start their vaccination programs against SARS-CoV-2 with the elderly, alongside the healthcare personnel and high-risk individuals [ 37 ]. Children seem indeed fairly exempt from severe forms of COVID-19 illness [ 38 ], although there have been reports on cardiac abnormalities that should not be underestimated [ 39 ].…”
Section: Spotlight On Original Articlesmentioning
confidence: 99%
“…
A systematic review and meta-analysis of children with coronavirus disease 2019 (COVID-19) [ 1 ] Cui X, et al., J Med Virol 2020 Summary: The authors conducted a systematic review and meta-analysis of articles reporting on pediatric cases of coronavirus disease 2019 (COVID-19) due to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. This article focused on the clinical presentation of COVID-19, including demographic characteristics, disease severity, reported symptoms, laboratory findings and imaging results.
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mentioning
confidence: 99%