2013
DOI: 10.2174/1874325001307010103
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Abstract: Introduction: Surgical management of Giant Cell Tumor of Bone of the distal radius (GCTDR) remains controversial due to risk of local recurrence (LR) offset by functional limitations which result from en-bloc resection. This study aims to determine the oncologic and functional outcomes of wide excision (WE) vs intralesional curettage (IC) of GCTDR.Methods: A complete search of the applicable literature was done. Included studies reported on patients from the same cohort who were surgically treated for GCTDR … Show more

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Cited by 41 publications
(32 citation statements)
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References 15 publications
(35 reference statements)
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“…A total of 11% (three of 27) of our patients experienced a local recurrence, which is comparable to that published in other studies and analyzed in recent meta-analyses [23,34]. In contrast, local recurrence after intralesional excision is as high as 31% [23,34].…”
Section: Discussionsupporting
confidence: 87%
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“…A total of 11% (three of 27) of our patients experienced a local recurrence, which is comparable to that published in other studies and analyzed in recent meta-analyses [23,34]. In contrast, local recurrence after intralesional excision is as high as 31% [23,34].…”
Section: Discussionsupporting
confidence: 87%
“…As such the defects created are particularly amenable to reconstruction with autogenous structural ICBG. Some authors favor the use of vascularized fibula grafts for the benefits of prompt bony union, the option to include skin to address soft tissue defects, and durability of the reconstruction [8,25,34]. On the other hand, the use of nonvascularized fibular grafts has the advantage of being less technically demanding.…”
Section: Discussionmentioning
confidence: 99%
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“…Liu et al (10) reported that patients in the intralesional excision group exhibited a higher recurrence rate, particularly for Campanacci's III Grade GCT compared with the en bloc resection group (10). Pazionis et al (11) reported that the odds of local recurrence were three times less in the en bloc resection group (n=60) compared with the intralesional excision group (n=81). Considering the high local recurrence risk of curettage, the 23 patients with Campanacci's grade II and III GCT of the distal radius and ulna were all treated with en bloc resection, and only one patient (1/23; 4.3%) relapsed.…”
Section: Discussionmentioning
confidence: 99%
“…Numerous previous studies have identified the distal radius and ulna as being particularly prone to recurrence. To date, the ideal treatment methods for GCTs of the distal ulna and radius remain controversial (10)(11)(12). En bloc resection of GCT provides lower rates of recurrences, which also sacrifices the joint, results in a major reconstruction, and the functional outcomes are questionable.…”
Section: Introductionmentioning
confidence: 99%