A Study of Vitamin D and Its Correlation With Severity and Complication of Congestive Heart Failure: A Systematic Review

Hazique, Mohammad; Khan, Kokab Irfan; Ramesh, Prasana; Kanagalingam, Suthasenthuran; Haq, FNU Zargham Ul; Srinivasan, Nishok Victory; Khan, Aujala Irfan; Mashat, Ghadi D; Khan, Safeera

doi:10.7759/cureus.28873

Cited by 5 publications

(3 citation statements)

References 30 publications

(48 reference statements)

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“…Patients with HF exhibiting low vitamin D levels tend to experience unfavorable outcomes, aligning with established clinical correlations and biomarkers [147]. In the context of HF affecting myocardial cells, the surplus of ionized calcium (Ca2) detrimentally impacts the contraction and relaxation of the heart [148].…”

Section: The Role Of Vitamin D In Heart Failurementioning

confidence: 86%

Vitamin D: A Bridge between Kidney and Heart

Secondulfo,

Visco,

Virtuoso

et al. 2024

Preprint

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Chronic kidney disease (CKD) and cardiovascular disease (CVD) are highly prevalent conditions, each significantly contributing to the global burden of morbidity and mortality. CVD and CKD share a great number of common risk factor, such as hypertension, diabetes, obesity, and smoking among others. Their relationship extends beyond these factors, encompassing intricate interplay between the two systems. Within this complex network of pathophysiological processes, vitamin D has emerged as a potential linchpin, exerting influence over diverse physiological pathways implicated in both CKD and CVD. In recent years, scientific exploration has unveiled a close connection between these two prevalent conditions and vitamin D, a crucial hormone traditionally recognized for its role in bone health. This article aims to provide an extensive review of vitamin D's multifaceted and expanding actions concerning its involvement in CKD and CVD.

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Section: The Role Of Vitamin D In Heart Failurementioning

confidence: 86%

Vitamin D: A Bridge between Kidney and Heart

Secondulfo,

Visco,

Virtuoso

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

“…Patients with HF exhibiting low vitamin D levels tend to experience unfavorable outcomes, aligning with established clinical correlations and biomarkers [154]. In the context of HF affecting myocardial cells, the surplus of ionized calcium (Ca2) detrimentally impacts the contraction and relaxation of the heart [155].…”

Section: The Role Of Vitamin D In Heart Failurementioning

confidence: 86%

Vitamin D: A Bridge between Kidney and Heart

Secondulfo,

Visco,

Virtuoso

et al. 2024

Life

View full text Add to dashboard Cite

Chronic kidney disease (CKD) and cardiovascular disease (CVD) are highly prevalent conditions, each significantly contributing to the global burden of morbidity and mortality. CVD and CKD share a great number of common risk factors, such as hypertension, diabetes, obesity, and smoking, among others. Their relationship extends beyond these factors, encompassing intricate interplay between the two systems. Within this complex network of pathophysiological processes, vitamin D has emerged as a potential linchpin, exerting influence over diverse physiological pathways implicated in both CKD and CVD. In recent years, scientific exploration has unveiled a close connection between these two prevalent conditions and vitamin D, a crucial hormone traditionally recognized for its role in bone health. This article aims to provide an extensive review of vitamin D’s multifaceted and expanding actions concerning its involvement in CKD and CVD.

show abstract

“…There is a need for long-term, fully-enrolled, randomized, placebo-controlled studies of high-dose vitamin D3 supplementation in patients with CHF, caused by left ventricular systolic dysfunction. The possibility of long-term advantages of vitamin D administration is suggested [149].…”

Section: Systematic Reviewmentioning

confidence: 99%

Frailty and the Interactions between Skeletal Muscle, Bone, and Adipose Tissue-Impact on Cardiovascular Disease and Possible Therapeutic Measures

Soto

Pérez-Torres

Rubio-Ruiz

et al. 2023

IJMS

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Frailty is a global health problem that impacts clinical practice. It is complex, having a physical and a cognitive component, and it is the result of many contributing factors. Frail patients have oxidative stress and elevated proinflammatory cytokines. Frailty impairs many systems and results in a reduced physiological reserve and increased vulnerability to stress. It is related to aging and to cardiovascular diseases (CVD). There are few studies on the genetic factors of frailty, but epigenetic clocks determine age and frailty. In contrast, there is genetic overlap of frailty with cardiovascular disease and its risk factors. Frailty is not yet considered a risk factor for CVD. It is accompanied by a loss and/or poor functioning of muscle mass, which depends on fiber protein content, resulting from the balance between protein breakdown and synthesis. Bone fragility is also implied, and there is a crosstalk between adipocytes, myocytes, and bone. The identification and assessment of frailty is difficult, without there being a standard instrument to identify or treat it. Measures to prevent its progression include exercises, as well as supplementing the diet with vitamin D and K, calcium, and testosterone. In conclusion, more research is needed to better understand frailty and to avoid complications in CVD.

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A Study of Vitamin D and Its Correlation With Severity and Complication of Congestive Heart Failure: A Systematic Review

Cited by 5 publications

References 30 publications

Vitamin D: A Bridge between Kidney and Heart

Vitamin D: A Bridge between Kidney and Heart

Vitamin D: A Bridge between Kidney and Heart

Frailty and the Interactions between Skeletal Muscle, Bone, and Adipose Tissue-Impact on Cardiovascular Disease and Possible Therapeutic Measures

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