A Study of the Skin in Five Hundred Cases of Diabetes

Greenwood, Arthur M.

doi:10.1001/jama.1927.02690100036009

Cited by 69 publications

(21 citation statements)

References 6 publications

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“…Green wood et al claimed 2.4% of diabetics had psoriasis. 8 These are several Indian studies indicating presence of relationship between the two diseases. Psoriasis and diabetes mellitus had been variously reported in literature as 2.4% to 5.7%.…”

Section: Psoriasismentioning

confidence: 97%

“…According to Greenwood AM et al the lesions caused by staphylococcus aureus are commoner in diabetics than in non diabetics it is possible that this incidence indicates in the balance of bacterial flora favouring the multiplication of potentially pathogenic gram positive cocci. 8 Rayfeild et al also quotes that there is diminution of bactericidal activity for staphylococcus aureus and e. coli in diabetics. 18 It is also suggested that disturbed fluid balance rather than increased sugar content of tissues also contribute to the predisposition of diabetes to bacterial infection.…”

Section: Laboratory Investigationsmentioning

confidence: 99%

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A study of cutaneous manifestations associated with diabetes mellitus

Kadam¹,

Soni²,

Phatale

et al. 2016

Int J Adv Med

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Background: Diabetes mellitus is a fairly common medical disorder that involves almost every specialty in its spectrum of clinical manifestation, and up to 1/3 rd of patients with diabetes mellitus are estimated to have cutaneous changes. In other words using broadest criteria all subjects with diabetes will diabetes will develop cutaneous manifestations of this disease. Methods: A total of 100 diabetic patients with cutaneous manifestations, who attended skin OPD at Civil Hospital, Belgaum, Karnataka, India and K.L.E'S Hospital and Medical Research Centre, were randomly selected. The present study was conducted over a period of 22 months from March 1995 to December 1996. Total 100 cases were included in this study. The male to female ratio is 1.6:1 approximately. Detailed history, physical examination, cutaneous and mucous membrane involvement examination was done. Diabetes Mellitus was confirmed by urine sugar and blood sugar estimation. The diagnosis of diabetes mellitus was done on the basis of criteria laid down by national diabetic data group. Urine and blood sugar estimation was done in all the cases. Results: Fungal infections were common cutaneous manifestation followed by bacterial infections and generalized pruritus. Those patients who were on oral hypoglycaemic drugs, insulin therapy found to have photodermatitis and localized lipoatrophy. The common associated skin diseases with diabetes mellitus were fungal infection (38%) and viral infections (2%). Unexplained generalized pruritus was observed in (17%) cases, followed by pruritus ani is (3%) and prurigo simplex in (1%). Cutaneous markers of diabetes i.e acrochordons were observed in 17% cases. The other manifestations observed were lichen planus (6%), PLE (3%), psoriasis (3%), vitiligo (2%), Kyrles disease (2%), infected eczema (2%), scabies (2%), lichen simplex chronicus (2%) and pemphigus vulgaris (1%). Conclusions:The physicians should be aware of cutaneous manifestations in diabetes mellitus. Where the ignorance of skin manifestations in diabetes or improper treatment may makes the condition worse. The early detection and early treatment of common skin manifestations in diabetes will prevent further complications or ineffectiveness due to treatment especially in cases of carbuncle, extensive tinea corporis, psoriasis, lichen planus, macro and micro angiopathies, trohic ulcers etc. A well-controlled diabetes by drugs, diet and exercise will allow the patient to lead a normal life like any other normal individuals.

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Section: Psoriasismentioning

confidence: 97%

Section: Laboratory Investigationsmentioning

confidence: 99%

A study of cutaneous manifestations associated with diabetes mellitus

Kadam¹,

Soni²,

Phatale

et al. 2016

Int J Adv Med

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“…Since diabetic women have a high incidence of anogenital pruritic and inflammatory reac tions [3,4], we think that diabetes mellitus may play an important role in causing labial adhesions.…”

Section: Introductionmentioning

confidence: 99%

Labial Adhesions in a Diabetic Woman

et al. 1986

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This paper reports a 72-year-old woman with labial adhesions, who complained of difficulty in urination and terminal dribbling. The adhesions were surgically dissected with success. Diabetes mellitus in addition to poor perineal hygiene seem to have made her susceptible to the recurrent vulvitis which led to labial adhesions. This case implies the significance of detecting diabetes mellitus as a contributory factor for labial adhesions.

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“…Greenwood showed that 2.5% of psoriasis had diabetes which was 10 times more than the control group in his study. 12 Najdaw et al found eczema or dermatitis as the commonest skin disorder in 25.9% of cases. 13 Anand showed that 8.88% of psoriasis patients had diabetes.…”

mentioning

confidence: 98%

“…A report by Greenwood found xanthelasma palpebrarum in 9 of 500 diabetics, an incidence of 1.8%. 12 Granuloma annulare was detected in 3 patients (0.90%). The association of granuloma annulare and diabetes mellitus is controversial.…”

mentioning

confidence: 99%

Cutaneous manifestations of endocrine disorders

Sampath¹,

Haritha²,

Mahesh³

2018

Int J Res Dermatol

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Background: It is a well-known fact that the skin is referred to as a window or mirror to the body. The present study was undertaken to know the spectrum of cutaneous manifestations in endocrinological disorders.Methods: A total of 500 patients with endocrinological disorders attending the Medical and Dermatology OPD at Dr. PSIMS&RF were studied. Among the 500 cases studied, 417 patients had diabetes, 81 cases had thyroid disorder and 2 patients had Addison’s disease.Results: Most common dermatoses observed in patients with diabetes mellitus were infections {(fungal 25.3%), bacterial (6.92%), viral (5.42%)} followed by eczemas (13.2%), psoriasis (8.13%). Among 81 patients with thyroid disease, 78 patients were hypothyroid and 3 patients had hyperthyroidism and skin manifestations were observed in 55 (67%) of the patients with thyroid disorders. Most common dermatoses observed in patients with hypothyroidism were fungal infections (23.07%), urticaria (19.23%), xerosis (13.46%), bacterial infections (13.46%), psoriasis (11.53%). All 3 hyperthyroid patients have shown skin manifestations. 2 patients had diffuse hair loss and 1 patient had vitiligo. 2 cases of Addison’s disease were observed and both of them showed diffuse hyperpigmentation with accentuation over palmar creases, knuckles and gums.Conclusions: The present study shows the wide range of skin lesions in patients with endocrinological disorders paerticularly diabetes mellitus and thyroid disease. Through knowledge of the associated skin lesions helps in early diagnosis of underlying endocrine abnormality and thereby appropriate treatment provided at the earliest helps in preventing complications.

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A Study of the Skin in Five Hundred Cases of Diabetes

Cited by 69 publications

References 6 publications

A study of cutaneous manifestations associated with diabetes mellitus

A study of cutaneous manifestations associated with diabetes mellitus

Labial Adhesions in a Diabetic Woman

Cutaneous manifestations of endocrine disorders

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