A study of prevalence of Vitamin D deficiency among pregnant women and its impact on feto maternal outcome

Shailaja, N; Krishna, Kirtan; Krishna, Lingaraj; Bhat, Burhan; Suma, Harumichi; Reddy, Surekha

doi:10.18203/2320-1770.ijrcog20160880

Cited by 7 publications

(7 citation statements)

References 19 publications

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“…But the difference between the two groups was not significant statistically. In our study maternal complications were more in vitamin D deficient groups, in agreement with by Nageshu S et al 6 NICU admission was needed in 34% babies. Out of 68 NICU admissions 67 (95.6%) were from the deficient group, whereas there was no NICU admission in babies born to mothers with sufficient vitamin D levels.…”

Section: Discussionsupporting

confidence: 92%

To Study the Prevalence of Vitamin D Deficiency in Third Trimester and Feto-Maternal Outcome.

Dagar

Gupta

Jindal

et al. 2022

ijmsdr

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Aim: To estimate the prevalence of vitamin D deficiency in third trimester and itscorrelation with feto-maternal outcome Material and Methods: Present study was conducted 200 pregnant women who were admitted to the labor room in the third trimester in the department of Obstetrics & Gynecology of Maharishi Markandeshwar Medical College and Hospital, Solan (H.P.) for delivery after fulfilling the inclusion & exclusion criteria. Detailed history including complete demographic information, past medical history, dietary history, previous menstrual & obstetric history, any antenatal complications. Delivery details including mode of delivery, birth weight and APGAR scores were recorded on the proforma. Serum vitamin D was estimated fromthe maternal blood sample. Vitamin D deﬁciency was deﬁned as 25(OH) D levels in blood less than 20 ng/ml, and insufficiency of vitamin D was deﬁned as 25(OH) D levels between 20-30 ng/ml.Results: In this study, there was a high prevalence of vitamin D deficiency (93.5%) in the pregnant women though there was no significant difference in socio-demographic factors in the deficient and non-deficient group. Present study showed that the proportion of vitamin D deficient pregnant women having maternal complications and NICU admission was statistically significant as compared to the non-deficient group (p=0.0109) and (p=0.0384) respectively. Conclusion: Maternal complications, increased cesarean section rate and NICU admission weremore associated with hypovitaminosis D but any causal relationship between vitaminD deficiency and pregnancy complications was not found in this study design. Wepropose that vitamin D supplementation is simple and economical, and hence weshould incorporate vitamin D testing, increase its awareness and treat its deficiency inadolescence, pre-conceptional period or 1st trimester to avoid maternal complicationsand poor fetal outcome. Keywords: Vitamin D Deficiency, Third trimester, Fetal outcome, Maternal outcomex

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Section: Discussionsupporting

confidence: 92%

To Study the Prevalence of Vitamin D Deficiency in Third Trimester and Feto-Maternal Outcome.

Dagar

Gupta

Jindal

et al. 2022

ijmsdr

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“…97.94% versus 94.04%. Similar results were also observed in studies conducted by Nageshu S et al, Dave A et al, Prasad D et al, Chauhan N et al 1,6,7 Vitamin D deficiency predisposes to low birth weights in babies. Table 4 depicts the distribution of subjects according to NICU admissions of their babies.…”

Section: Discussionsupporting

confidence: 86%

“…As per this study, 98.10% of the subjects whose babies were admitted in the NICU, had vitamin D deficiency, which is similar to the studies conducted by Nageshu S et al and Prasad D et al i.e., 87.5% and 90% respectively. 1,6 Vitamin D deficiency makes the fetal heart more vulnerable to fetal distress or birth asphyxia, thus increasing the NICU admissions in babies.…”

Section: Discussionmentioning

confidence: 99%

Vitamin D deficiency and adverse fetal outcome

Chandel¹,

Sharma²,

Mittal³

et al. 2020

Int J Reprod Contracept Obstet Gynecol

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Background: Vitamin D deficiency is recognized as the most untreated nutritional deficiency in the world. It is plausible that vitamin D deficiency could make the fetal heart more vulnerable to distress/birth asphyxia. Vitamin D deficiency has been hypothesized to be associated with low birth weight, low Apgar score at birth, higher rates of still births and admission to NICU. The aim of present study was to study prevalence of vitamin D deficiency in pregnancy and evaluate perinatal outcome.Methods: The study was conducted in the department of obstetrics and gynecology, Kamla Nehru Hospital, Shimla, India over a period of 12 months. Six hundred women were included in the study.Results: All the mothers who had still births suffered from vitamin D deficiency and the severe vitamin D deficiency was there in 90.91% (30) of these subjects. Severe vitamin D deficiency was seen in 78.95% (75) of the subjects having babies with birth weights <2.5 kg compared to 61.16% (288) subjects of the other group.Conclusions: Adverse fetal outcome are more common in vitamin D deficient group.

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“…From this study it is clear that maternal complications like gestational hypertension, preeclampsia-eclampsia, GDM and preterm labour are more common in subjects having vitamin D deficiency (98.61%, 100%, 100% 98.64% respectively). Similar results are there in the studies conducted by Nageshu N et al, Chauhan N et al and Prasad D et al [4][5][6] Whereas GDM was seen equally in both vitamin D sufficient and vitamin D deficient group (50% versus 50%) in the study by Dave A et al and gestational hypertension was more in the vitamin D sufficient group (61.90%). 7 This disparity may be due to insufficient evidence because of low sample size.…”

Section: Discussionsupporting

confidence: 86%

Vitamin D deficiency and maternal complications

Chandel¹,

Mittal²,

Sharma³

et al. 2020

Int J Reprod Contracept Obstet Gynecol

View full text Add to dashboard Cite

Background: Vitamin D deficiency is prevalent in India, a finding that is unexpected in a tropical country with abundant sunshine. Vitamin D deficiency is recognized as the most untreated nutritional deficiency currently in the world. Several studies reported the relationship between maternal vitamin D deficiency and adverse maternal and fetal outcomes including gestational diabetes, preeclampsia, preterm labour, low birth weight and increased rate of caesarean section.Methods: The study was conducted in the department of obstetrics and gynecology, Kamla Nehru Hospital, Shimla, Himachal Pradesh, India over a period of 12 months. Six hundred women were included in the study.Results: Forty-eight (8%) subjects developed preeclampsia-eclampsia syndrome, of which none had sufficient vitamin D levels, whereas 48 (100%) subjects had vitamin D deficiency.Conclusions: Maternal antenatal complications are more common in vitamin D deficient group.

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A study of prevalence of Vitamin D deficiency among pregnant women and its impact on feto maternal outcome

Cited by 7 publications

References 19 publications

To Study the Prevalence of Vitamin D Deficiency in Third Trimester and Feto-Maternal Outcome.

To Study the Prevalence of Vitamin D Deficiency in Third Trimester and Feto-Maternal Outcome.

Vitamin D deficiency and adverse fetal outcome

Vitamin D deficiency and maternal complications

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