A Spindle-Cell Myoepithelioma of the Lacrimal Gland

Myoepithelioma of the Orbital Apex and Middle Cranial Fossa: Case Report and Review of the Literature

“…29 Intraorbital myoepitheliomas are thought to arise from the lacrimal gland in most cases, although in one report it was thought to arise from the soft tissues of the lower eye lid. 2,3,[21][22][23][24][25]27 In the case described here, the tumour did not have any continuity with the lacrimal gland neither on preoperative imaging (Figure 1) nor at the time of surgery and there was no involvement of the eyelid. Rather, it appears to have arisen from the sphenoid ridge and extended into the orbit via the SOF.…”

Myoepithelioma of the Orbital Apex and Middle Cranial Fossa: Case Report and Review of the Literature

“…29 Intraorbital myoepitheliomas are thought to arise from the lacrimal gland in most cases, although in one report it was thought to arise from the soft tissues of the lower eye lid. 2,3,[21][22][23][24][25]27 In the case described here, the tumour did not have any continuity with the lacrimal gland neither on preoperative imaging (Figure 1) nor at the time of surgery and there was no involvement of the eyelid. Rather, it appears to have arisen from the sphenoid ridge and extended into the orbit via the SOF.…”

Lacrimal myoepithelial carcinoma ex recurrent pleomorphic adenoma: A clinicopathological report and review of the literature

“…usually remain asymptomatic until they produce a mass effect. The most frequently presenting symptoms are painless proptosis, progressive periorbital swelling, diplopia, and blindness (2,(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18).…”

Myoepithelioma of the lacrimal gland: Report of a case with potentially malignant transformation

“…As normal myoepithelial cells, neoplastic myoepithelial cells are generally considered to share both muscular and epithelial characteristics, and have been shown to be immunoreactive for cytokeratin, EMA, m‐actin, and sm‐actin. 5–7,12,14–17 Jones et al , however, pointed out in a study on salivary gland tumors that many myoepitheliomas were not immunoreactive for sm‐actin. 17 The present tumor showed immunoreactivities for vimentin and S‐100, but not for either cytokeratin, EMA, m‐actin, sm‐actin, or any other antigen examined.…”

Myoepithelioma of the Orbital Apex and Middle Cranial Fossa: Case Report and Review of the Literature

“…29 Intraorbital myoepitheliomas are thought to arise from the lacrimal gland in most cases, although in one report it was thought to arise from the soft tissues of the lower eye lid. 2,3,[21][22][23][24][25]27 In the case described here, the tumour did not have any continuity with the lacrimal gland neither on preoperative imaging (Figure 1) nor at the time of surgery and there was no involvement of the eyelid. Rather, it appears to have arisen from the sphenoid ridge and extended into the orbit via the SOF.…”

Lacrimal myoepithelial carcinoma ex recurrent pleomorphic adenoma: A clinicopathological report and review of the literature

“…usually remain asymptomatic until they produce a mass effect. The most frequently presenting symptoms are painless proptosis, progressive periorbital swelling, diplopia, and blindness (2,(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18).…”

Myoepithelioma of the lacrimal gland: Report of a case with potentially malignant transformation

“…As normal myoepithelial cells, neoplastic myoepithelial cells are generally considered to share both muscular and epithelial characteristics, and have been shown to be immunoreactive for cytokeratin, EMA, m‐actin, and sm‐actin. 5–7,12,14–17 Jones et al , however, pointed out in a study on salivary gland tumors that many myoepitheliomas were not immunoreactive for sm‐actin. 17 The present tumor showed immunoreactivities for vimentin and S‐100, but not for either cytokeratin, EMA, m‐actin, sm‐actin, or any other antigen examined.…”

Myoepithelioma of the Orbital Apex and Middle Cranial Fossa: Case Report and Review of the Literature

“…29 Intraorbital myoepitheliomas are thought to arise from the lacrimal gland in most cases, although in one report it was thought to arise from the soft tissues of the lower eye lid. 2,3,[21][22][23][24][25]27 In the case described here, the tumour did not have any continuity with the lacrimal gland neither on preoperative imaging (Figure 1) nor at the time of surgery and there was no involvement of the eyelid. Rather, it appears to have arisen from the sphenoid ridge and extended into the orbit via the SOF.…”

Lacrimal myoepithelial carcinoma ex recurrent pleomorphic adenoma: A clinicopathological report and review of the literature

“…usually remain asymptomatic until they produce a mass effect. The most frequently presenting symptoms are painless proptosis, progressive periorbital swelling, diplopia, and blindness (2,(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18).…”

Myoepithelioma of the lacrimal gland: Report of a case with potentially malignant transformation

“…As normal myoepithelial cells, neoplastic myoepithelial cells are generally considered to share both muscular and epithelial characteristics, and have been shown to be immunoreactive for cytokeratin, EMA, m‐actin, and sm‐actin. 5–7,12,14–17 Jones et al , however, pointed out in a study on salivary gland tumors that many myoepitheliomas were not immunoreactive for sm‐actin. 17 The present tumor showed immunoreactivities for vimentin and S‐100, but not for either cytokeratin, EMA, m‐actin, sm‐actin, or any other antigen examined.…”