A single-institution review of lacrimal gland biopsies between 1962 and 2017

Choi, Catherine J.; Tran, Ann Q; Anagnostopoulos, Apostolos G.; Zhou, Hongning; Tse, David T.; Dubovy, Sander R.

doi:10.1080/01676830.2022.2052113

Cited by 6 publications

(3 citation statements)

References 14 publications

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“…LGACC is the most common tumor in lacrimal gland and occurred in all age groups [43] . The average age of onset was 40y, and most cases affected females.…”

Section: Discussionmentioning

confidence: 99%

Treatment of lacrimal gland adenoid cystic carcinoma: a systematic review and Meta-analysis

Yan,

Wang,

et al. 2024

Int J Ophthalmol

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AIM: To evaluate lacrimal gland adenoid cystic carcinoma (LGACC) of prognosis in patients who underwent different treatment regimens. METHODS: We searched PubMed, EMBASE, and the Cochrane Library for studies done on the treatment of LGACC, between January 1987 and April 2022. A Meta-analysis was conducted to pool the 5-year overall survival rate (OR), and the 5-year recurrence rate (RR) and 5-year metastasis rate (MR) were assessed. RESULTS: The 30 studies involved 585 patients were included in the Meta-analysis. The pooled 5-year OR with surgery alone was 50%, the 5-year RR was 63%, and the 5-year MR was 34%. The pooled 5-year OR with surgery and adjuvant radiotherapy combined was 67% (95%CI 61%,73%), the 5-year RR was 41%, and the 5-year MR was 35%. The pooled 5-year OR with surgery and adjuvant chemoradiotherapy combined was 72% (95%CI 59%, 84%), the 5-year RR was 48%, and the 5-year MR was 36%. The pooled 5-year OR with surgery, intra-arterial cytoreductive chemotherapy, and adjuvant chemoradiotherapy combined was 78% (95%CI 68%, 89%), the 5-year RR was 15%, and the 5-year MR was 27%. CONCLUSION: Comprehensive treatment is more effective than surgery alone. Surgery combined with intra-arterial chemotherapy and adjuvant chemoradiotherapy seems to add value to the therapeutic effect of comprehensive treatment of LGACC but further high-quality research is required to validate this.

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“…LGACC is the most common tumor in lacrimal gland and occurred in all age groups [43] . The average age of onset was 40y, and most cases affected females.…”

Section: Discussionmentioning

confidence: 99%

Treatment of lacrimal gland adenoid cystic carcinoma: a systematic review and Meta-analysis

Yan,

Wang,

et al. 2024

Int J Ophthalmol

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“…LIP is a kind of non-speci c type of orbital in ammatory pseudotumor, occurring among adults [19]. The basic pathological changes of LIP include in ammatory cell in ltration, brosclerosis, and cell degeneration [20,21]. The choice of treatment methods are closely related to the pathological tissues classi cation.…”

Section: Discussionmentioning

confidence: 99%

“…LGTs represent 3-18% of all orbital tumors commonly [1][2][3]. There are four main groups of lacrimal gland lesions: in ammatory, lymphoid, primary epithelial tumors, and metastatic tumor [4]. Traditionally, it has been reported that approximately 50% of LGTs originated from epithelial elements and 50% are of nonepithelial origin.…”

Section: Introductionmentioning

confidence: 99%

Histogram Analysis of Computed Tomography Images to Differentiate Lacrimal Lymphoma and Lacrimal Inflammatory Pseudotumor

Zhang

Yuan

Wan

et al. 2023

Preprint

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Background To investigate the value of the histogram analysis to identify between lacrimal lymphoma(LL) and lacrimal inflammatory pseudotumor(LIP). Methods CT images of 30 patients with LL and 43 patients with LIP were analyzed for imaging features and histogram parameters. Tumor morphology and histogram parameters of LL and LIP were compared. Receiver operating characteristic (ROC) analysis of area under the curve (AUC), sensitivity, and specificity were used to measure the differential diagnostic efficacy of these parameters. Results Compared those in LIP group，lesions in LL group were more bilateral and had clearer boundary (P= .036 and .000, respectively), while no significant difference of other CT features was found between groups(all P> .05). The variance of the LIP group were greater than that of the LL group, with statistically significant differences (P=.000). The mean, skewness, kurtosis, 1th, 10th, and 50th percentiles of the LL group were greater than those of the LIP group, with statistically significant differences (all P＜.05). Acceptable discrimination was detected between LL and LIP with mean, variance, skewness, kurtosis, 1th, 10th, and 50th percentiles alone (AUC =0.789, 0.825, 0.716, 0.762, 0.624, 0.719, and 0.666 respectively). The combination of these histogram parameters yielded excellent discrimination between LL and LIP(AUC = 0.961), with sensitivity and specificity values greater than 0.800. Conclusions Histogram analysis of CT images is feasible for differentiating LL from LIP. It can be used as a supplementary tool for differentiating the lacrimal tumors.

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The lateral fornix orbitotomy: a novel surgical corridor to lacrimal gland lesions

Mombaerts,

Moe,

Kakizaki

2024

Graefes Arch Clin Exp Ophthalmol

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A single-institution review of lacrimal gland biopsies between 1962 and 2017

Cited by 6 publications

References 14 publications

Treatment of lacrimal gland adenoid cystic carcinoma: a systematic review and Meta-analysis

Treatment of lacrimal gland adenoid cystic carcinoma: a systematic review and Meta-analysis

Histogram Analysis of Computed Tomography Images to Differentiate Lacrimal Lymphoma and Lacrimal Inflammatory Pseudotumor

The lateral fornix orbitotomy: a novel surgical corridor to lacrimal gland lesions

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