A simple click generated probe for highly selective sequential recognition of Cu(II) and pyrophosphate

A novel and simple solvent-dependent fluorescent probe based on a click generated 8-aminoquinoline–steroid conjugate for multi-detection of Cu(ii), oxalate and pyrophosphate

“…Consequently, the development of uorescent probes for the facile detection of Cu 2+ , C 2 O 4 2À and P 2 O 7 4À is very important to control their concentration levels in the biosphere and avoid severe damage to humans. Although a number of dual functional uorescent probes for Cu 2+ /C 2 O 4 2À and Cu 2+ /P 2 O 7 4À have been developed, [28][29][30][31][32][33][34][35][36][37][38] these chemosensors for anions are always based upon the use of metal complex receptors, especially dinuclear Cu 2+ complex, or the metal displacement approaches. Using these indirect sensing out-put methods, the detection of C 2 O 4 2À or P 2 O 7 4À is very much dependent on the design of an appropriate metal coordinative complex and the affinity of the metal ion for its complementary anion, which could be affected by various factors and is less easily realizable.…”

“…42 And 8-aminoquinoline and its derivatives are well-known excellent building blocks for constructing highly selective uorescent sensors of transition metal cations. 36,[43][44][45][46] Meanwhile, the bridging 1,2,3-triazole group was introduced via click chemistry in order to offer not only a straightforward strategy for the linkage of various functionalities, but also a potential binding site for both metal ions and anions, 47,48 which is very benecial for multi-target analysis.…”

A Novel 1,8-Disubstituted Pyrene-Based Fluorescent Probe for Subsequent Detection of Cu2+ and Pyrophosphate

“…Fluorescence intensity change of probe L-Cu 2＋ and L-Cu 2＋ ＋PPi in different pH (λ ex ＝366nm) 化合物 1 [25] 和化合物 2 [34] 按照文献方法合成.…”

“…Huang 等 [24] 利用商品化的 4-(5-氯-2-吡啶基偶氮)-1,3-苯二胺在 六次甲基四胺介质中(黄色溶液)与 Cu 2＋ 结合后呈现红 色, 形成的络合物继续滴加 PPi 变成蓝绿色, 通过裸眼 即可接力识别 Cu 2＋ 和 PPi. 我们 [25] 曾合成了一种喹啉衍 生物在二甲基亚砜/水(V∶V＝1∶1, HEPES, pH＝7.4)中…”

Design and Synthesis of a Dinuclear Copper(II) Probe for Selective Fluorescence Sensing of Pyrophosphate

“…In particular, the metal complexes based on strong coordination ability with anions were considered to be ideal candidates for PPi recognition [22]. Many of previously reported Cu(II)-based PPi sensors detected the PPi anions by releasing quenching copper(II) ion [23][24][25][26][27]; the probes based on PPi binding recognition mechanism were still rare [28][29][30][31].…”