2019
DOI: 10.1080/09540105.2019.1612331
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A sensitive lateral flow immunoassay for the multiple residues of five adamantanes

Abstract: Adamantanes (ADAs) are tricyclic decane saturated derivatives, which are used in the protection against the influenza virus. However, their abuse in animal husbandry has affected human health. To help prevent drug resistance and protect food safety, a rapid, portable, sensitive, and reliable method for onsite detection of ADAs was developed. Herein, we have produced a broadspecificity anti-ADAs monoclonal antibody (mAb), the subclass of which is IgG 2b , and its affinity constant is 7.25 × 10 9 L/mol. From thi… Show more

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Cited by 11 publications
(2 citation statements)
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“…The most commonly used LFIA method employs gold nanoparticles (AuNPs) as reporters for colorimetric detection. A LFIA method using a broadly specific anti-adamantanes monoclonal antibody has been developed for five adamantanes, with visual LODs of 0.1–10 μg/kg (similar to the results of ELISA) [ 34 ]. To further improve the sensitivity of LFIA, other labels such as fluorescent nanoparticles have been employed in LFIA fabrication.…”
Section: Rapid Multi-residue Detection Methods Based On Different mentioning
confidence: 99%
“…The most commonly used LFIA method employs gold nanoparticles (AuNPs) as reporters for colorimetric detection. A LFIA method using a broadly specific anti-adamantanes monoclonal antibody has been developed for five adamantanes, with visual LODs of 0.1–10 μg/kg (similar to the results of ELISA) [ 34 ]. To further improve the sensitivity of LFIA, other labels such as fluorescent nanoparticles have been employed in LFIA fabrication.…”
Section: Rapid Multi-residue Detection Methods Based On Different mentioning
confidence: 99%
“…Such tests for 2-8 analytes are widely used to determine antibiotics in milk, mycotoxins in grain, etc. and described in a series of recent publications [12][13][14][15][16].…”
Section: Introductionmentioning
confidence: 99%