A rhodamine based fluorescent trivalent sensor (Fe³⁺, Al³⁺, Cr³⁺) with potential applications for live cell imaging and combinational logic circuits and memory devices

Abstract

A novel sensor (HL5) recognizes sensitively and selectively trivalent metal ions M3+ (M = Al, Fe and Cr) with prominent enhancement in emission intensities with logic gate circuits and memory devices with living cell imaging application.

Recent Advances on Iron(III) Selective Fluorescent Probes with Possible Applications in Bioimaging

“…The turn-on colorimetric and fluorescent sensor 25 shows the LOD 0.768 μM Fe 3+ and bioimage Fe 3+ ions in live HeLa cells [33]. The probe 26 detects Fe 3+ , Al 3+ , and Cr 3+ with the estimated LOD of 0.29, 0.34, and 0.31 μM, respectively [34]. The probe 26 has been applied to mimic the Boolean logic gates with two and four inputs.…”

Anthrone‐spirolactam and quinoline hybrid based sensor for selective fluorescent detection of Fe3+ ions

“…The stretching vibration of C=O str (lactam) at 1716 and 1,650 cm −1 is shifted to 1,716 and 1,640 cm −1 with relatively high transmittance, which indicates the involvement of the carbonyl oxygen atom (lactam unit) and confirms the formation of lactam ring-closed complex. [21,26,62,63] The stretching vibration of the imine C=N group of RSD-1 at 1596 cm −1 shifts to the lower frequency of 1587 cm −1 in the complex system with a shift of about 11 cm −1 and a reduction in sharpness with high transmittance, which demonstrates the interaction of Fe 3+ ions with the nitrogen atom of imine.…”

“…There was an ambiguity about whether the molecule might undergo a ring-opening of lactam in the Fe complex state as the ligand RSD-1 resembles rhodamine derivatives [64][65][66][67] (there are a few reports on rhodamine-based sensors that followed the spirolactam ring closed chelation mechanism). [68][69][70][71][72][73] In the case of spirolactam ring-opened sensors, the complex system showed the formation of a new band over 550 or 600 nm ranges in absorbance and emission.…”

New rhodamine B-based chromo-fluorogenic probes for highly selective detection of aluminium(iii) ions and their application in living cell imaging

“…[16][17][18][19][20] Apparently, the reasonable design and preparation of effective biocompatible Al 3+ uorescent chemosensors are urgent problems need to be solved currently. [21][22][23][24] Considering the weak coordination ability and strong tendency to hydrolysis of Al 3+ ions, small-molecular uorescent probes with bright chromophore and multidentate coordination sites are highly promising. Recent studies reveal that the rhodamine-based probes are regarded as ideal candidates for the "off-on" uorescent sensors owing to the excellent photophysical properties such as remarkable photostability, high uorescence quantum yields, special response mechanism, strong anti-interference ability and long emission wavelength.…”