A Review on Exploring the Phytochemical and Pharmacological Significance of Indigofera astragalina

Abstract

Indigofera astragalina, a versatile medicinal plant, has gained significant attention because of its rich phytochemical composition and diverse therapeutic properties. I. astragalina contains sterols, phenolics, alkaloids, and flavonoids, making it ideal for a variety of therapeutic purposes. In this review, an in-depth look at the phytoconstituents and their biological activity is presented. The anti-microbial properties of the plant extracts have been demonstrated against drug-resistant Enterococcus and Staphylococcus aureus strains resistant to vancomycin and methicillin. Moreover, the plant exhibits moderate to potent anti-protozoal activity against Trypanosoma brucei and weak anti-protozoal activity against Plasmodium falciparum. In various cancer cell lines, astragalin extracts have demonstrated significant cytotoxic effects, suggesting their potential as anti-cancer agents. Due to its high phenolic content, the plant has an antioxidant effect, which has contributed to its traditional use for managing oxidative stress. In addition, I. astragalina is packed with essential amino acids, minerals (such as iron, manganese, and zinc), and vitamins. The comprehensive analysis of I. astragalina emphasizes its important role in drug discovery, nutrition, and healthcare, as well as its tremendous therapeutic potential.