A Review of Treating Depression in Diabetes: Emerging Findings

Markowitz, Sarah; Gonzalez, Jeffrey S.; Wilkinson, Jesse L.; Safren, Steven A.

doi:10.1016/j.psym.2010.11.007

Cited by 204 publications

(157 citation statements)

References 99 publications

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“…Depression treatment for diabetic patients can result in improved mental health, but the evidence is less clear that intervention will lead to improved glycemic control or improvement in other diabetesrelated outcomes (32,33), although interventions that integrate both depression and diabetes treatment appear to hold promise (34,35).…”

Section: Discussionmentioning

confidence: 99%

“…664 (11) 77 (12) 587 (11) 54 (13) 609 (11) 32 (11) 631 ( (35) 140 (29) 1,519 (35) 106 (31) 1,553 (35) 71 (32) 1,588 (35) Obese 1,078 (22) 150 (31) 928 (22) 108 (32) 970 (22) 67 ( 962 (20) 207 (40) 755 (18) 142 (41) 820 (18) 87 (39) 875 ( (18) 169 (29) 877 (17) 123 (31) 923 (17) 78 (30) 968 (18) No insurance 109 (2) 20 (3) 89 (2) 15 (4) 94 (2) 8 (3) 101 ( and depression remained in the multivariate model (P = 0.001; data not shown).…”

Section: Depression Using Continuous Phq-8 Scorementioning

confidence: 99%

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Depression in Adults in the T1D Exchange Clinic Registry

et al. 2014

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OBJECTIVELittle is known about the frequency of depression in adults with type 1 diabetes (T1D) or its relationship to diabetes outcomes. The T1D Exchange clinic registry allowed us to explore depression in a large, heterogeneous sample. RESEARCH DESIGN AND METHODSParticipants ‡18 years old (N = 6,172; median age 34 years; median diabetes duration 16 years; 55% female; and 89% non-Hispanic white) completed the eight-item Patient Health Questionnaire (PHQ-8), a validated, reliable measure of current depression. Probable major depression was defined in four ways: PHQ-8 ‡10, PHQ-8 ‡12, per diagnostic algorithm, and as a continuous variable. Characteristics and clinical outcomes of those with and without depression were compared using logistic and linear regression models. RESULTSA total of 4.6-10.3% of participants were classified as probable major depression depending on how defined. Participants classified as depressed were more likely female, nonwhite race/ethnicity, to have a lower household income and lower education level, to exercise less often, to miss insulin doses, and to have one or more complications (neuropathy, nephropathy, treatment for retinopathy, or cardiovascular/cerebrovascular disease) (all P < 0.01). HbA 1c was higher in the depressed versus not depressed groups (8.4 6 1.7% [68 6 8.6 mmol/mol] vs. 7.8 6 1.4% [62 6 15.3 mmol/mol]; P < 0.001). Occurrence of one or more diabetic ketoacidosis events (11 vs. 4%; P < 0.001) and one or more severe hypoglycemic events (18 vs. 9%; P < 0.001) in the past 3 months was higher among depressed participants. CONCLUSIONSIn the T1D Exchange clinic registry, adults with probable major depression have worse clinical outcomes than those not depressed. Whether identification and treatment of depression improves diabetes outcomes requires study. Depression is common in T1D, and better identification and treatment of this comorbid condition is needed.The prevalence of depression is almost two times higher in persons with diabetes than it is in the general population (1-3). Not only do persons with diabetes have an increased risk of developing depression (4), but persons with depression have an increased risk of developing diabetes (5), which may relate to their use of antidepressants (6) or other biological or psychosocial factors associated with diabetes. Depression in diabetes is a particular concern because it is associated with poorer glycemic control (7) and regimen adherence (8), greater morbidity and mortality

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Section: Discussionmentioning

confidence: 99%

Section: Depression Using Continuous Phq-8 Scorementioning

confidence: 99%

Depression in Adults in the T1D Exchange Clinic Registry

et al. 2014

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“…[41] [42] Emerging research investigating improvements in adherence and glycemic control as the result of treatments tailored solely toward addressing co-morbid internalizing disorders, such as depression or generalized anxiety disorder, reveal similar results. [42] [43] Keeping in mind the clear inhibiting role of externalizing and internalizing problems (highlighted below) on adherence, and the importance of adherence in glycemic regulation, future treatment plans for youth with T1D should incorporate concurrent psychological therapy. Parent reported internalizing disorders are believed to be present in approximately 28% of individuals with diabetes [44] [45] and, similar to externalizing disorders, co-morbid presenting internalizing disorders have been associated with a worse prognosis in youth with T1D.…”

Section: The Challenges Of Type 1 Diabetesmentioning

confidence: 99%

Contributing Factors to Poor Adherence and Glycemic Control in Pediatric Type 1 Diabetes: Facilitating a Move Toward Telehealth

McNamara¹,

Reid²,

Freedland³

et al. 2011

Type 1 Diabetes - Complications, Pathogenesis, and Alternative Treatments

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“…В частности, меня интересует, как хронические психические заболевания, та-кие как депрессия, могут влиять на течение и лечение хронических соматических заболева-ний, таких как сахарный диабет, а также на-сколько различается взаимное влияние этих за-болеваний в разных популяциях пациентов. В последние годы появилось много научной ли-тературы, которая свидетельствует о том, что у некоторых пациентов недостаточный кон-троль сахарного диабета может быть обуслов-лен депрессией, которая часто сопутствует не-которым хроническим заболеваниям [6]. Кроме того, представляет интерес, насколько у боль-ных с впервые выявленным сахарным диабетом учитываются их предпочтения и предпочтения членов их семьи при выборе тактики лечения, как, например, это происходит при оказании паллиативной помощи.…”

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A Continued International Parternship in Family Medicine

Jackson

Г²

2016

Rossiĭskiĭ semeĭnyĭ vrach

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Кафедра семейной медицины университета Айовы длительно и плодотворно сотрудничает с кафедрой семейной медицины Северо-Западного государственного медицинского университета имени И.И. Меч-никова, которая была организована 20 лет назад. Такие отношения являются очень важными для обуче-ния ординаторов и непрерывного профессионального развития врачей. В октябре 2016 г. три препо-давателя и один ординатор (автор данной статьи) прилетели в Санкт-Петербург, чтобы участвовать в юбилейной конференции кафедры семейной медицины и встретиться со своими российскими колле-гами. Кроме того, автор статьи в течение двух недель находился на стажировке в Центре семейной медицины СЗГМУ им. И.И. Мечникова, чтобы познакомиться с особенностями работы семейных врачей и выполнить небольшой научный проект. В статье описаны особенности подготовки семейных врачей в США, впечатления о конференции, приводится краткое описание нового совместного исследователь-ского проекта, а также другие детали, связанные с опытом, полученным в период стажировки в России.Ключевые слова: семейная медицина, международное партнерство, ординатура, сахарный диабет, депрессия, стажировка. A CONTINUED INTERNATIONAL PARTERNSHIP IN FAMILY MEDICINEJ.G. Jackson University of Iowa, Iowa City, USA The Department of Family Medicine of University of Iowa has a long and collaborative relationship with the Department of Family Medicine of North-Western State Medical University named after I.I. Mechnikov that started over 20 years ago. Relationships like these are very valuable for resident education and continued professional development. In October, 2016 3 attending physicians and 1 resident (the author of this article) were able to visit St. Petersburg to participate in a conference and visit the department. I stayed for an additional two weeks as part of my residency training to participate in clinical, academic and research activities. Below is an outline of the educational and training requirements for doctors of family medicine in the US, comments on the conference, a brief summary of a new research project with investigators from both sites and other details of my experience in Russia.Keywords: family medicine, international partnership, residency, diabetes, depression, training.Даже в моем маленьком городке, который называется Айова-Сити и находится в центре одного из сельских штатов Америки, пациенты, обращающиеся за медицинской помощью к се-мейному врачу, имеют массу особенностей, свя-занных с местом проживания, религией, язы-ком, культурой, что ежедневно оказывает вли-яние на характер общения. Конечно, это не особенность Айовы, а обычная практика, кото-рая встречается везде. В связи с этим овладе-ние «общекультурной компетенцией» или «культурно-информированный уход» -это важная составляющая учебных программ на всей территории США с начала XXI в. [1].Международное партнерство -чрезвычай-но мощный инструмент образования, который делает «культурную компетенцию» востребо-ванной для понимания молодым врачом, обуча-ющимся в ординатуре, особенностей пациентов в разных стр...

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A Review of Treating Depression in Diabetes: Emerging Findings

Cited by 204 publications

References 99 publications

Depression in Adults in the T1D Exchange Clinic Registry

Depression in Adults in the T1D Exchange Clinic Registry

Contributing Factors to Poor Adherence and Glycemic Control in Pediatric Type 1 Diabetes: Facilitating a Move Toward Telehealth

A Continued International Parternship in Family Medicine

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