A Review for Artificial Intelligence Based Protein Subcellular Localization
Hanyu Xiao,
Yijin Zou,
Jieqiong Wang
et al.
Abstract:Proteins need to be located in appropriate spatiotemporal contexts to carry out their diverse biological functions. Mislocalized proteins may lead to a broad range of diseases, such as cancer and Alzheimer’s disease. Knowing where a target protein resides within a cell will give insights into tailored drug design for a disease. As the gold validation standard, the conventional wet lab uses fluorescent microscopy imaging, immunoelectron microscopy, and fluorescent biomarker tags for protein subcellular location… Show more
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