A retrospective investigation of twenty-five cases with periocular pilomatrixoma

Abstract

Purpose Pilomatrixoma is an uncommon benign skin tumor, developing from hair follicle matrix. It consistently presents in the head and neck region patients with pediatric predominance, from infancy to senior. Thus far, few case series studies have been focused on the periocular lesions that involve the eyelid and eyebrow. In the present study, we carried out a case series with 25 patients of periocular pilomatrixoma. Methods Records from the Hospital Information System (HIS) of our hospital were reviewed retrospectively between the years 2009 and 2020 to search for all patients that were diagnosed as pilomatrixoma of eyelid or eyebrow. All patients received excision in the Department of Ophthalmology and histological examinations in the Department of Pathology. Patients’ information and characterization of tumors features were recorded and analyzed. Results These clinical conditions were mostly found in female patients in their early twenties. All tumors developed at upper eyelids or eyebrows and both right and left sides were equally affected. Basophilic cells and shadow cells were the basic components of the lesions, with or without calcification and foreign body giant cells. Complete surgical resection was the essential therapeutical approach for this disease and no recurrence or malignant transformations were noticed upon follow-up. Conclusion The findings of current case series analysis are in concordance with the clinical and histopathological features of periocular pilomatrixoma.