A retrospective analysis of acute organophosphorus poisoning cases admitted to the tertiary care teaching hospital in South India

Kumar, Meriga Rajesh; Kumar, GP Vignan; Babu, P Ramesh; Kumar, S Satish; Subrahmanyam, B. V.; Veeraprasad, M; Rammohan, Pathapati; Srinivas, Mangala; Agrawal, Amit

doi:10.4103/1596-3519.129876

Cited by 29 publications

(40 citation statements)

References 29 publications

(36 reference statements)

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“…Incidence of childhood poisoning reported in various studies ranged from 0.33% to 7.6%. Cause of poisoning varies with age, gender, education, and cultural background and it also shows seasonal variations [7] The results of the present study showed median age of 4 years among our patients, mean age was 6.71±5.43 years. The highest percentage of cases (56.1%) occurred at age of 1-5 years.…”

Section: Discussionsupporting

confidence: 46%

Pattern of Acute Toxicity Among Children at Zagazig University Hospitals in 2017: (Clinical and Demographic Data)

Sarhan

Ameen

Saleh

2018

Egyptian Society of Clinical Toxicology Journal

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Background: Acute poisoning in children is still an important public health problem and represents a frequent cause of admission in poisoning treatment and emergency units. Objectives: The aim of this (retrospective) study was to describe various characteristics of poisoning in children; (clinical and epidemiological data.) Patients and methods: Sixty six cases of children (27 males, 39 females) up to 16 years old for suspected toxicity were studied retrospectively in a one year-long period starting from January until Decemper 2017 with exclusion of patients with acute food poisoning. Detailed patients history was taken; their age, residence, date of admission, time, route and form of poisoning as well as type of causative agents. Also we analyzed their clinical presentation, lines of treatment and their outcome. Results: We found that female gender and rural residents were more affected, most cases were accidental, while suicidal and homicidal cases were less frequent. We found that time lapse from intoxication or ingestion of poison to hospital arrival was significantly less in survivors as compared to expired children. The route in most cases was by ingestion. Organophosphorus compounds were the commonest agents followed by medications. Other agents in reduced frequency were: rodenticides, kerosene, corrosives, snake bites, phenols and toothpaste. Neurological manifestations were more common than gastro intestinal, cardiac and pulmonary manifestations. Conclusion: Acute poisoning either accidental or suicidal is still a significant cause of hospital admission among children in our locality. The study recommended increasing awareness about potential toxins as well as appropriate storage of drugs and household cleaning agents to decrease the incidence of accidental poisoning. It also recommended as possible early management by supportive measures and antidotes to improve the prognosis of cases.

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Section: Discussionsupporting

confidence: 46%

Pattern of Acute Toxicity Among Children at Zagazig University Hospitals in 2017: (Clinical and Demographic Data)

Sarhan

Ameen

Saleh

2018

Egyptian Society of Clinical Toxicology Journal

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“…10 The age distribution of APP in females suggests that the highest proportion of cases was found in the age group 20-29 years. This is broadly consistent with findings from studies in India, [46][47] [50][51] may also contribute to increase risk for suicidal attempts.…”

Section: Discussionsupporting

confidence: 91%

“…Organophosphates (OPs) emerged as the single most important group of agents responsible for poisoning in females in this study. This pattern is consistent with studies conducted in India, 47 Sri Lanka 18 and Nepal 49 and reflects the widespread use of organophosphate insecticides in Tanzania. 52 Previous research suggest that, broadly speaking, usage patterns appear to be correlated with APP in Tanzania.…”

Section: Discussionsupporting

confidence: 90%

Acute Pesticide Poisoning amongst adolescent girls and women in Northern Tanzania

Lekei

Ngowi

Kapeleka

et al. 2020

Preprint

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Background: Acute pesticide poisoning (APP) is reported to affect community health worldwide but its burden in Tanzania is unknown particularly in women. This study examines APP involving adult females and adolescent girls 10 to 19 years in 3 regions of Tanzania which are famous for coffee and vegetable productionMethods. Over the period of 12 months, health facility-based surveillance for cases of APP was implemented in 10 Tanzanian healthcare facilities in 2006. Results. The study identified 108 APP cases of whom 31 (28.7%) occurred amongst adolescent girls. Suicide was the leading poisoning circumstances (60.2%) and the most vulnerable women were 20-29 years old who comprised 38.4% of all cases with suicide as circumstance.Organophosphates (OPs), zinc phosphide, paraquat and endosulfan were common amongst known reported poisoning agents. The annual APP incidence, mortality and Case Fatality Rate for women were 5.1/100,000, 0.2/100,000 and 3.7/100, respectivelyConclusion. APP amongst women in Tanzania is common and this call for diverse preventive interventions to reduce poisoning incidents.

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“…The age distribution of APP in females suggests that the highest proportion of cases was found in the age group 20-29 years. This is broadly consistent with findings from studies in India [46,47], South Africa [48] and Nepal [49] although the Nepalese and South African studies included females in the younger age range. Females aged 15 to 40 years may be involved in pesticide handling and may attempt suicide using pesticides as a result of easy access to toxic chemicals.…”

Section: Discussionsupporting

confidence: 90%

Acute pesticide poisoning amongst adolescent girls and women in northern Tanzania

et al. 2020

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Background: Acute pesticide poisoning (APP) is reported to affect community health worldwide but its burden in Tanzania is unknown particularly in women. This study examines APP involving adult females and adolescent girls 10 to 19 years in 3 regions of Tanzania which are famous for coffee and vegetable production. Methods: Over the period of 12 months, health facility-based surveillance for cases of APP was implemented in 10 Tanzanian healthcare facilities in 2006. Results: The study identified 108 APP cases of whom 31 (28.7%) occurred amongst adolescent girls. Suicide was the leading poisoning circumstances (60.2%) and the most vulnerable women were 20-29 years old who comprised 38.4% of all cases with suicide as circumstance. Organophosphates (OPs), zinc phosphide, paraquat and endosulfan were common amongst known reported poisoning agents. The annual APP incidence, mortality and Case Fatality Rate for women were 5.1/100,000, 0.2/100, 000 and 3.7/100, respectively. Conclusion: APP amongst women in Tanzania is common and this call for diverse preventive interventions to reduce poisoning incidents.

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A retrospective analysis of acute organophosphorus poisoning cases admitted to the tertiary care teaching hospital in South India

Cited by 29 publications

References 29 publications

Pattern of Acute Toxicity Among Children at Zagazig University Hospitals in 2017: (Clinical and Demographic Data)

Pattern of Acute Toxicity Among Children at Zagazig University Hospitals in 2017: (Clinical and Demographic Data)

Acute Pesticide Poisoning amongst adolescent girls and women in Northern Tanzania

Acute pesticide poisoning amongst adolescent girls and women in northern Tanzania

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