A Repressor Complex Governs the Integration of Flowering Signals in Arabidopsis

Li, Dan; Liu, Chang; Shen, Lisha; Wu, Yang; Chen, Hongyan; Robertson, Masumi; Helliwell, Chris A.; Ito, Toshiro; Meyerowitz, Elliot M.; Yu, Hao

doi:10.1016/j.devcel.2008.05.002

Cited by 425 publications

(507 citation statements)

References 45 publications

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“…Though there is a second GI homoeolog in both papaya and grape, they are highly diverged. Likewise, SHORT VEGETATIVE PHASE (SVP), a floral repressor in the thermosensory pathway 39 , has only two Brassica orthologs, likely produced by the recent WGT, and low copy number in other plants with the few paralogs being highly diverged in sequence (e.g. <53% similarity in protein sequences) (Fig S7.2F5).…”

Section: Stabilizing the Genome Of A Mesohexaploidmentioning

confidence: 99%

The genome of the mesopolyploid crop species Brassica rapa

Wang¹,

Wang²,

Wang³

et al. 2011

Nat Genet

1,793

1,813

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The genome of the mesopolyploid crop species Brassica rapaThe Brassica rapa Genome Sequencing Project Consortium 1 Abstract:The Brassicaceae family which includes Arabidopsis thaliana, is a natural priority for reaching beyond botanical models to more deeply sample angiosperm genomic and functional diversity. Here we report the draft genome sequence and its annoation of Brassica rapa, one of the two ancestral species of oilseed rape. We modeled 41,174 protein-coding genes in the B. rapa genome. B. rapa has experienced only the second genome triplication reported to date, with its close relationship to A. thaliana providing a useful outgroup for investigating many consequences of triplication for its structural and functional evolution. The extent of gene loss (fractionation) among triplicated genome segments varies, with one copy containing a greater proportion of genes expected to have been present in its ancestor (70%) than the remaining two (46% and 36%). Both a generally rapid evolutionary rate, and specific copy number amplifications of particular gene families, may contribute to the remarkable propensity of Brassica species for the development of new morphological variants. The B. rapa genome provides a new resource for comparative and evolutionary analysis of the Brassicaceae genomes and also a platform for genetic improvement of Brassica oil and vegetable crops.2

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Section: Stabilizing the Genome Of A Mesohexaploidmentioning

confidence: 99%

The genome of the mesopolyploid crop species Brassica rapa

Wang¹,

Wang²,

Wang³

et al. 2011

Nat Genet

1,793

1,813

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“…Under short days, SOC1 appears also to be the major integrator of flowering time stimulation in response to the phytohormone GA (Blázquez and Weigel, 1999;Moon et al, 2003). SOC1 expression is furthermore repressed by the MADS box transcription factor FLOWERING LOCUS C, which controls flowering in response to long cold periods (vernalization) and acts together with the MADS box transcription factor SHORT VEGETA-TIVE PHASE (Hartmann et al, 2000;Li et al, 2008;Tao et al, 2012). Additionally, SOC1 expression is controlled by an age-dependent regulatory system that involves SQUAMOSA PROMOTER BINDING PROTEIN-LIKE (SPL) transcription factors and their antagonistic micro-RNA regulator miRNA156 .…”

mentioning

confidence: 99%

Cross-Repressive Interactions between SOC1 and the GATAs GNC and GNL/CGA1 in the Control of Greening, Cold Tolerance, and Flowering Time in Arabidopsis

Richter¹,

Bastakis²,

2013

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The paralogous and functionally redundant GATA transcription factors GNC (for GATA, NITRATE-INDUCIBLE, CARBON-METABOLISM INVOLVED) and GNL/CGA1 (for GNC-LIKE/CYTOKININ-RESPONSIVE GATA FACTOR1) from Arabidopsis (Arabidopsis thaliana) promote greening and repress flowering downstream from the phytohormone gibberellin. The target genes of GNC and GNL with regard to flowering time control have not been identified as yet. Here, we show by genetic and molecular analysis that the two GATA factors act upstream from the flowering time regulator SUPPRESSOR OF OVEREXPRESSION OF CONSTANS1 (SOC1) to directly repress SOC1 expression and thereby repress flowering. Interestingly, this analysis inversely also reveals that the MADS box transcription factor SOC1 directly represses GNC and GNL expression to control cold tolerance and greening, two further physiological processes that are under the control of SOC1. In summary, these findings support the case of a cross-repressive interaction between the GATA factors GNC and GNL and the MADS box transcription factor SOC1 in flowering time control on the one side and greening and cold tolerance on the other that may be governed by the various signaling inputs that are integrated at the level of SOC1 expression.

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“…Long-distance movement of FT protein from leaves to the shoot apex through the phloem system allows FT to interact with a bZIP transcription factor FD in the shoot apical meristem for activating floral meristem identity genes 10,12,13 . SOC1 is expressed in leaves and shoot apical meristems in response to multiple flowering pathways, and encodes a MADS-box transcription factor that acts as a key flowering promoter through regulating another floral meristem identity gene, LEAFY 2-5, [14][15][16] . Although several studies indicate that CO activates SOC1 either directly or indirectly via FT in the photoperiod pathway 3,10,17,18 , so far there is no evidence to support direct regulation of SOC1 transcription by CO or FT.…”

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confidence: 99%

Nuclear factor Y-mediated H3K27me3 demethylation of the SOC1 locus orchestrates flowering responses of Arabidopsis

et al. 2014

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Nuclear factor Y (NF-Y) is a conserved heterotrimeric transcription factor complex that binds to the CCAAT motifs within the promoter region of many genes. In plants, a large number of genes code for variants of each NF-YA, B or C subunit that can assemble in a combinatorial fashion. Here, we report the discovery of an Arabidopsis NF-Y complex that exerts epigenetic control over flowering time by integrating environmental and developmental signals. We show that NF-Y interacts with CONSTANS in the photoperiod pathway and DELLAs in the gibberellin pathway, to directly regulate the transcription of SOC1, a major floral pathway integrator. This NF-Y complex binds to a unique cis-element within the SOC1 promoter to modulate trimethylated H3K27 levels, partly through a H3K27 demethylase REF6. Our findings establish NF-Y complexes as critical mediators of epigenetic marks that regulate the response to environmental or intrinsic signals in plants.

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A Repressor Complex Governs the Integration of Flowering Signals in Arabidopsis

Cited by 425 publications

References 45 publications

The genome of the mesopolyploid crop species Brassica rapa

The genome of the mesopolyploid crop species Brassica rapa

Cross-Repressive Interactions between SOC1 and the GATAs GNC and GNL/CGA1 in the Control of Greening, Cold Tolerance, and Flowering Time in Arabidopsis

Nuclear factor Y-mediated H3K27me3 demethylation of the SOC1 locus orchestrates flowering responses of Arabidopsis

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