A Rare Thymoma Type Presenting as a Giant Intrathoracic Tumor: Lipofibroadenoma

Abstract

Type B1 thymoma (lipofibroadenoma) is extremely rare. The tumor is characterized by an organoid appearance rich in lymphocytes with medullary differentiation and perivascular spaces. A twenty-threeyear-old female patient was admitted to our clinic with complaints of chest pain and dyspnea for six months. Chest computed tomography showed solid and fatty components of masses 21×7 and 5×7 cm with clear borders in the right thoracic cavity. The patient underwent a posterolateral thoracotomy in which the mass, arising from the anterior mediastinum, was resected. Histopathological examination showed that the mass was Type B1 thymoma, and the patient was presented in light of the literature. Key Words: Lipofibroadenoma, Mediastinum, Thymoma ÖzetTip B1 timoma (lipofibroadenoma) oldukça nadirdir. Tümör medül-ler farklılaşma ve perivasküler aralık ile lenfositten zengin organoid bir görünümle karakterizedir. Yirmi üç yaşında bir bayan olgu altı ay önce başlayan göğüs ağrısı ve nefes darlığı şikâyetleri ile kliniğimize başvurdu. Toraks bilgisayarlı tomografide sağ torasik kavitede düz-gün kenarlı solid ve yağ dansiteleri içeren bir kitle (21×7, 5×7 cm) görüldü. Olguya uygulanan posterolateral torakotomide anterior mediastenden kaynaklanan bir kitle tespit edilip rezeke edildi. Histopatolojik inceleme Tip B1 timoma olarak bildirilen olgu literatür bilgileri ışığında sunuldu.

Giant Intrathoracic Mass in a Young Woman With Acute Kidney Injury

“…An autoimmune condition was reported in one patient. [1][2][3][4][5][6] The present patient is the first report of pure lipofibroadenoma accompanied by AAV. Although the direct link could not be confirmed, accidental cooccurrence of these two ultra rare diseases seems to be even less possible.…”

Successful Resection of Giant Mediastinal Lipofibroadenoma of the Thymus by Video-Assisted Thoracoscopic Surgery

“…Lipofibroadenoma shares some morphologic features of thymolipoma and resembles fibroadenoma of the breast [1]. The first two cases were described by Moran and colleagues [2] in 1994; thereafter, only three additional cases have been reported in the English literature [1,3,4]. Lipofibroadenoma has been described to be asymptomatic and incidentally discovered on routine chest roentgenogram studies or in the context of pneumonia.…”

Giant thymoma presenting as a large bilateral intrathoracic mass: A case report and a comparison between median sternotomy and hemiclamshell approach

“…The anterolateral thoracotomy was the operation of choice in some cases [ [9] , [10] , [11] , [12] ], allowing the extension of the incision to include a posterolateral or a hemiclamshell approach. Posterolateral thoracotomy was also used in three cases [ [13] , [14] , [15] ], but this approach has bad access to the anterior mediastinum. Because of that, it was followed in Ref.…”