A Rare Cause of Transient Proximal Tubule Dysfunction: COVID-19

Abstract

ABS TRACT Coronavirus disease-2019 (COVID-19), the plague of our time, affects many systems. Kidney involvement may cause acute kidney injury by affecting proximal tubules along with other probable sites. Although renal effects of COVID-19 have been reported in adults, pediatric data are limited. A five-year-old, previously healthy boy hospitalized for COVID-19 infection, developed polyuria on the 3 rd day of his admittance. Laboratory workup was compatible with proximal renal tubulopathy and normal clinical and laboratory status was achieved within 5 days with only conservative therapy. Laboratory findings were normal at the first month out-patient visit. We hypothesize that the transient proximal tubulopathy experienced in our case is related to COVID-19 infection. Clinicians should keep in mind the potential tubular involvement in children with COVID-19 infection.

COVID-19 in Special Patient Groups

“…Although using corticosteroids in addition to oxygen therapy reduces mortality, it can increase hyperglycemia, the need for insulin therapy, diabetic ketoacidosis, and hyperosmolar coma by increasing existing insulin resistance. The continuation of current insulin treatments, frequent blood glucose, and ketone monitoring are recommended in diabetic COVID-19 cases (30).…”