A rare case of necrotizing sialometaplasia of palate treated with intralesional steroid

Abstract

Necrotizing sialometaplasia is a rare, benign, inflammatory disease of minor salivary glands and is similar in appearance to malignant lesions. A rare case of necrotizing sialometaplasia in palate treated with intralesional steroids is presented. A 65-year-old male patient had an ulcerated lesion of approximately 1x2 cm in size near the midline in palate that had not healed for 2 weeks . The biopsy findings were in agreement with the diagnosis of necrotizing sialometaplasia. The patient was treated with a single dose of intralesional 40 mg triamcinolone acetonide. At the end of the second week, the lesion was completely healed. Necrotizing sialometaplasia is an inflammatory disease that can mimic malignancies. Spontaneous healing is possible, and occurs from 4 to 10 weeks. Intralesional steroid administration can be considered as a treatment option that accelerates healing in this rare disease.

Importância da biópsia incisional em lesões orais potencialmente malignas

“…Coba nog lu et al [3] acrescent a m como diagnóstico diferencial para a SMN o sarcoma secu ndá rio. A f i rma m que essa patolog ia é caracterizada por necrose lobular e metaplasia ductal e acinar e que normalmente existe uma infraestrutura inflamatória.…”

“…Por na superfície haver hiperplasia pseudoepiteliomatosa e metaplásica, faci l mente o cor rem er ro s no d i a g nó st ico, confundindo-se a SMN com o carcinoma de células escamosas. A mucosa residual celular com metaplasia escamosa ductal e acinar também sugere carcinoma mucoepidermoide [3].…”