A rare acute neck pain cause that can have misdiagnosis or missed diagnosis-crowned dens syndrome: description of two cases and a literature analysis

Qin, Xiaoping; Hu, Xiaofei; Wang, Qingzhen; Zeng, Jigang; Chen, Jie

doi:10.21037/qims-20-1347

Cited by 2 publications

(3 citation statements)

References 22 publications

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“…A case report by Oka et al summarized 69 cases from previous case reports and reported that in 50% of cases, the initial diagnosis was wrong. 5 Meanwhile, more than 30 case reports and clinical images have been published since 2010, [6][7][8][9][10][11][12][13][14] and CDS is frequently mentioned in Japanese medical books. We have the impression that we regularly diagnose and manage CDS, suggesting a perception gap between these previous studies and our clinical experience.…”

Section: Introductionmentioning

confidence: 99%

“…Meanwhile, more than 30 case reports and clinical images have been published since 2010, 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 and CDS is frequently mentioned in Japanese medical books. We have the impression that we regularly diagnose and manage CDS, suggesting a perception gap between these previous studies and our clinical experience.…”

Section: Introductionmentioning

confidence: 99%

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Crowned dens syndrome: A case series of 72 patients at eight teaching hospitals in Japan

Isono¹,

Kuno

Hozumi

et al. 2023

J of Gen and Family Med

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Background Crowned dens syndrome (CDS) is characterized by calcification around the odontoid process, accompanied by neck pain. Although CDS is supposedly rare, we regularly diagnose and manage this condition, indicating a perception gap between previous studies and our experience. The purpose of this study was to determine the annual incidence of CDS, time to diagnosis in CDS, as well as the features of CDS. Methods The study design was a retrospective case series study conducted at eight teaching hospitals in Japan. We identified CDS cases from April 2013–March 2015. CDS was diagnosed when patients had acute onset of neck pain and CT showed calcification around the dens and when other diagnoses were unlikely. Results Seventy‐two CDS cases were identified. Mean annual incidence was 4.6 ± 2.3 cases at each hospital. Among those with available data, 57 of 64 had limited rotation (89.1%). The diagnosis of CDS was made in general internal medicine or the emergency medicine department in 61 cases (84.7%). A total of 62 cases (86.1%) were diagnosed within 1 day of presentation, and the median time from initial presentation at the hospital to diagnosis was 0.0 days (25th–75th percentiles, 0.0–1.0). For treatment, NSAIDs were used in 56cases (77.8%) and acetaminophen in 20 cases (27.8%). Conclusion CDS might be more common than has been reported to date. Time to diagnosis of CDS was within 1 day of visiting a teaching hospital. Cervical motion restriction is common in CDS and may be useful in establishing the diagnosis.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Crowned dens syndrome: A case series of 72 patients at eight teaching hospitals in Japan

Isono¹,

Kuno

Hozumi

et al. 2023

J of Gen and Family Med

View full text Add to dashboard Cite

show abstract

“…Lesion structure between individuals exhibits a vast difference. Furthermore, even within the same human body, there is a considerable degree of variability in the morphology of tissues, and similarities between lesion tissues and normal tissues can be observed, easily leading to misdiagnosis and missed diagnosis [15]. 6.…”

mentioning

confidence: 99%

Symmetry GAN Detection Network: An Automatic One-Stage High-Accuracy Detection Network for Various Types of Lesions on CT Images

Zhang

et al. 2022

Symmetry

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Computed tomography (CT) is the first modern slice-imaging modality. Recent years have witnessed its widespread application and improvement in detecting and diagnosing related lesions. Nonetheless, there are several difficulties in detecting lesions in CT images: (1) image quality degrades as the radiation dose is reduced to decrease radiational injury to the human body; (2) image quality is frequently hampered by noise interference; (3) because of the complicated circumstances of diseased tissue, lesion pictures typically show complex shapes; (4) the difference between the orientated object and the background is not discernible. This paper proposes a symmetry GAN detection network based on a one-stage detection network to tackle the challenges mentioned above. This paper employs the DeepLesion dataset, containing 10,594 CT scans (studies) of 4427 unique patients. The symmetry GANs proposed in this research consist of two distinct GAN models that serve different functions. A generative model is introduced ahead of the backbone to increase the input CT image series to address the typical problem of small sample size in medical datasets. Afterward, GAN models are added to the attention extraction module to generate attention masks. Furthermore, experimental data indicate that this strategy has significantly improved the model’s robustness. Eventually, the proposed method reaches 0.9720, 0.9858, and 0.9833 on P, R, and mAP, on the validation set. The experimental outcome shows that the suggested model outperforms other comparison models. In addition to this innovation, we are inspired by the innovation of the ResNet model in terms of network depth. Thus, we propose parallel multi-activation functions, an optimization method in the network width. It is theoretically proven that by adding coefficients to each base activation function and performing a softmax function on all coefficients, parallel multi-activation functions can express a single activation function, which is a unique ability compared to others. Ultimately, our model outperforms all comparison models in terms of P, R, and mAP, achieving 0.9737, 0.9845, and 0.9841. In addition, we encapsulate the model and build a related iOS application to make the model more applicable. The suggested model also won the second prize in the 2021 Chinese Collegiate Computing Competition.

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A rare acute neck pain cause that can have misdiagnosis or missed diagnosis-crowned dens syndrome: description of two cases and a literature analysis

Abstract: rare acute neck pain cause that can have misdiagnosis or missed diagnosis-crowned dens syndrome: description of two cases and a literature analysis.

Cited by 2 publications

References 22 publications

Crowned dens syndrome: A case series of 72 patients at eight teaching hospitals in Japan

Crowned dens syndrome: A case series of 72 patients at eight teaching hospitals in Japan

Symmetry GAN Detection Network: An Automatic One-Stage High-Accuracy Detection Network for Various Types of Lesions on CT Images

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