A rapid method for the <i>in vivo</i> measurement of liver volume

Zoli, Marco; Pisi, P; Marchesini, Giulio; Bianchi, Giampaolo; Turci, Giulia; Pisi, E

doi:10.1111/j.1600-0676.1989.tb00393.x

Cited by 28 publications

(17 citation statements)

References 8 publications

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“…Liver volume estimation with abdominal helical CT has been reported to be very reliable. It has been regarded as the most accurate imaging technique for in vivo evaluation of organ volume and is considered the gold standard 19,20 . Volume measurements with CT have been used in large numbers of human patients with liver disease, because CT is easy, safe, and rapid 15,21 .…”

Section: Discussionmentioning

confidence: 99%

“…It has been regarded as the most accurate imaging technique for in vivo evaluation of organ volume and is considered the gold standard. 19,20 Volume measurements with CT have been used in large numbers of human patients with liver disease, because CT is easy, safe, and rapid. 15,21 CT also is capable of rapid and accurate measurements of liver volume and growth in small animals such as dogs.…”

Section: Discussionmentioning

confidence: 99%

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Hepatic Volume Measurements in Dogs with Extrahepatic Congenital Portosystemic Shunts before and after Surgical Attenuation

Kummeling¹,

Vrakking²,

Rothuizen³

et al. 2010

Veterinary Internal Medicne

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Background: In dogs with congenital portosystemic shunts (CPSS), the ability of the hypoplastic liver to grow is considered important for recovery after surgical shunt attenuation.Objectives: This study investigated hepatic growth after extrahepatic shunt attenuation in dogs using magnetic resonance imaging (MRI) and computed tomography (CT).Animals: Ten client-owned dogs with single extrahepatic CPSS. Methods: Abdominal MRI, CT, or both were performed before and 8 days, 1, and 2 months after shunt attenuation. Liver volumes were calculated from the areas of the MRI or CT images.Results: Before surgery, median liver volume was 18.2 cm 3 /kg body weight. Liver volume increased significantly after surgery. Growth was highest between days 0 and 8 and decreased afterward. Median liver volume was 28.8 cm 3 /kg at 2 months after attenuation. No significant differences in growth were found between dogs with complete or partial shunt closure or between dogs with complete or incomplete metabolic recovery. Volumes measured from consecutively performed MRI and CT images correlated well (r 5 0.980), but volumes from MRI images were significantly larger than volumes from CT images (6.8%; P 5 .008).Conclusion and Clinical Importance: After shunt attenuation, rapid normalization of liver size was observed. Hepatic growth was not decreased in dogs after partial closure of CPSS or in dogs with subclinical, persistent shunting 2 months after surgery. CT is the preferred imaging method for volumetric estimation because of speed.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Hepatic Volume Measurements in Dogs with Extrahepatic Congenital Portosystemic Shunts before and after Surgical Attenuation

Kummeling¹,

Vrakking²,

Rothuizen³

et al. 2010

Veterinary Internal Medicne

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“…Liver size is a significant indicator of the presence of a disease process . Knowledge of hepatic size is also important in surgical planning and follow‐up of treatments and interventions over time .…”

Section: Introductionmentioning

confidence: 99%

Ultrasound in the assessment of hepatomegaly: A simple technique to determine an enlarged liver using reliable and valid measurements

et al. 2016

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Introduction Knowledge of the size of the liver is an important factor in diagnosing liver disease. Hepatomegaly is a term used to describe a liver that is enlarged beyond its normal dimensions, and ultrasound is often a front line investigation in the suspicion of hepatomegaly. This study sought to develop a reference range for the size of the normal liver using a simple, reliable and valid measurement technique. Methods Two ultrasound images of the liver and a blood test were taken from 126 participants. Three simple linear measurements were taken from these two images and converted to a liver volume using a published equation. Results The reference range for liver volume in adults without liver pathology was found to be 1060–2223 cm3. Conclusion This new measurement technique and reference range is simple and easy to perform in the clinical environment. It has the potential to discriminate a liver normal in size to one with hepatomegaly.

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“…Knowledge of the size of the adult liver can be useful for many reasons. It can aid in the diagnosis of hepatomegaly, where the finding of an enlarged liver can cause a physician to look further for a disease process, or it can be used for surgical planning . A way to reliably repeat measurements of liver size can further be used to monitor disease progression or response to treatment over time .…”

Section: Introductionmentioning

confidence: 99%

“…It can aid in the diagnosis of hepatomegaly, where the finding of an enlarged liver can cause a physician to look further for a disease process, or it can be used for surgical planning. [1][2][3][4] A way to reliably repeat measurements of liver size can further be used to monitor disease progression or response to treatment over time. 2 For research purposes, it can be used to monitor the livers' response to an intervention over time, be it a lifestyle intervention (e.g.…”

Section: Introductionmentioning

confidence: 99%

The inter‐rater and intra‐rater reliability of a recently developed equation to determine liver volume using three simple two‐dimensional ultrasound measurements

Childs

Lamb

2018

Sonography

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Introduction A reliable way to measure the size of the adult liver is valuable for numerous reasons, including the diagnosis of disease and the tracking of disease or response to treatment or intervention over time. This study sought to determine the intra‐rater and inter‐rater reliability of a recently developed equation to calculate liver volume using three simple two‐dimensional (2D) ultrasound measurements: A dome to tip measurement in the midclavicular line (A), an anterior to posterior measurement in the midclavicular line (B) and an anterior to posterior measurement in the midline (C), placed into the equation 343.71 + [0.84 × A × B × C]. While the three measures have been shown to be reliable, it is also important to determine the reliability of the equation as there is potential for error to be magnified by the multiplication process. Methods Two examiners acquired two ultrasound images of the liver of each participant, performed the three measurements and calculated the liver volume using the equation. One examiner repeated the images and measurements. Results All measurements demonstrated high intra‐rater reliability [intra‐class correlation coefficient (ICCs) 0.851–0.972] with the volume equation having an ICC of 0.954 and limits of agreement of 178.7 cm3. All measurements also demonstrated high inter‐rater reliability (ICCs 0.761–0.954) with the volume equation having an ICC value of 0.918 and limits of agreement of 246.4 cm3. Conclusion The liver volume equation can be reliably performed by both the same rater and different raters.

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A rapid method for the in vivo measurement of liver volume

Cited by 28 publications

References 8 publications

Hepatic Volume Measurements in Dogs with Extrahepatic Congenital Portosystemic Shunts before and after Surgical Attenuation

Hepatic Volume Measurements in Dogs with Extrahepatic Congenital Portosystemic Shunts before and after Surgical Attenuation

Ultrasound in the assessment of hepatomegaly: A simple technique to determine an enlarged liver using reliable and valid measurements

The inter‐rater and intra‐rater reliability of a recently developed equation to determine liver volume using three simple two‐dimensional ultrasound measurements

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